Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.60 |
| ▸ | HTR2B | P41595 | 1/20 | 0.60 |
| ▸ | RXRA | P19793 | 2/20 | 0.54 |
| ▸ | RXRB | P28702 | 2/20 | 0.54 |
| ▸ | RXRG | P48443 | 2/20 | 0.54 |
| ▸ | MRGPRX4 | Q96LA9 | 11/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1332171 | 0.86 | HTR2C (0.59) | HTR2CSLC6A4HTR2BRXRARXRB | |
| SCHEMBL1333232 | 0.83 | HTR2C (0.58) | HTR2CSLC6A4HTR2BRXRARXRB | |
| SCHEMBL18703359 | 0.83 | MRGPRX4 (0.61) | HTR2CSLC6A4HTR2BRXRARXRB | |
| SCHEMBL1331639 | 0.83 | HTR2C (0.58) | HTR2CSLC6A4HTR2BRXRARXRB | |
| SCHEMBL385216 | 0.82 | HTR2C (0.58) | HTR2CSLC6A4HTR2BRXRARXRB | |
| SCHEMBL28074627 | 0.82 | HTR2C (0.55) | HTR2CSLC6A4HTR2BRXRARXRB | |
| SCHEMBL4150404 | 0.81 | HTR2C (0.56) | HTR2CSLC6A4HTR2BRXRARXRB | |
| SCHEMBL6080280 | 0.81 | MRGPRX4 (0.57) | HTR2CSLC6A4HTR2BRXRARXRB | |
| SCHEMBL1332170 | 0.81 | SLC6A4 (0.56) | HTR2CSLC6A4HTR2BRXRARXRB | |
| SCHEMBL31020080 | 0.81 | RXRA (0.57) | HTR2CSLC6A4HTR2BRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670763-A1 | CYCLOPENTENE COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005037793-A1 | CYCLOPENTENE COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2005-04-28 | — | — | WO | disclosed |