Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | RXRA | P19793 | 2/20 | 0.55 |
| ▸ | RXRB | P28702 | 2/20 | 0.55 |
| ▸ | RXRG | P48443 | 2/20 | 0.55 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31020080 | 0.83 | RXRA (0.57) | HTR2CSLC6A4HTR2BRXRARXRB | |
| SCHEMBL12167392 | 0.83 | HTR2C (0.56) | HTR2CSLC6A4HTR2BRXRARXRB | |
| SCHEMBL17305160 | 0.83 | HTR2C (0.56) | HTR2CSLC6A4HTR2BRXRARXRB | |
| SCHEMBL30573038 | 0.83 | HTR2C (0.56) | HTR2CSLC6A4HTR2BRXRARXRB | |
| SCHEMBL5730837 | 0.83 | HTR2C (0.60) | HTR2CSLC6A4HTR2BRXRARXRB | |
| SCHEMBL3918382 | 0.83 | HTR2C (0.56) | HTR2CSLC6A4HTR2BRXRARXRB | |
| SCHEMBL538233 | 0.83 | RXRA (0.57) | HTR2CSLC6A4HTR2BRXRARXRB | |
| SCHEMBL1332171 | 0.81 | HTR2C (0.59) | HTR2CSLC6A4HTR2BRXRARXRB | |
| SCHEMBL1331639 | 0.81 | HTR2C (0.58) | HTR2CSLC6A4HTR2BRXRARXRB | |
| SCHEMBL18703359 | 0.81 | MRGPRX4 (0.61) | HTR2CSLC6A4HTR2BRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105461635-B | Phenylpiperazine derivatives and its application method and purposes | 乳源瑶族自治县大众药品贸易有限公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-105461635-A | Phenylpiperazine derivatives, using method thereof and uses of the derivatives | RUYUAN YAO AUTONOMOUS COUNTY DAZHONG MEDICINE TRADE CO LTD | 2016-04-06 | — | — | CN | disclosed |
| US-8394986-B2 | Phenoxiacetic acid derivatives | ASTRAZENECA AB (GB) | 2013-03-12 | — | — | US | disclosed |
| US-20110281898-A1 | PHENOXIACETIC ACID DERIVATIVES | ASTRAZENECA AB | 2011-11-17 | — | — | US | disclosed |
| US-8003703-B2 | Phenoxiacetic acid derivatives | ASTRAZENECA AB (SE) | 2011-08-23 | — | — | US | disclosed |
| EP-1660431-B1 | PHENOXYACETIC ACID DERIVATIVES | ASTRAZENECA AB (SE) | 2009-04-01 | — | — | EP | disclosed |
| US-20060293352-A1 | Phenoxiacetic acid derivatives | ASTRAZENECA AB (SE) | 2006-12-28 | — | — | US | disclosed |
| EP-1660431-A2 | PHENOXYACETIC ACID DERIVATIVES | Astrazeneca AB (SE) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005018529-A2 | PHENOXIACETIC ACID DERIVATIVES | ASTRAZENECA AB (SE) | 2005-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060293352-A1 | Phenoxiacetic acid derivatives | HRH2, HRH1, HCAR2 | HTR2C 119/4885SLC6A4 2808/4885HTR2B 234/4885 |
| US-20110281898-A1 | PHENOXIACETIC ACID DERIVATIVES | HIF1A, HPD, HIF1AN | HTR2C 325/4885SLC6A4 1152/4885HTR2B 910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.