SCHEMBL385216

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1332171	0.84	HTR2C (0.59)	HTR2CSLC6A4HTR2BRXRARXRB
	SCHEMBL5730837	0.82	HTR2C (0.60)	HTR2CSLC6A4HTR2BRXRARXRB
	SCHEMBL18703359	0.81	MRGPRX4 (0.61)	HTR2CSLC6A4HTR2BRXRARXRB
	SCHEMBL17141539	0.80	HTR2C (0.54)	HTR2CSLC6A4HTR2BRXRARXRB
	SCHEMBL15922822	0.80	HTR1A (0.65)	L3MBTL1HTR1AADRA1DADRA1AADRA1B
	SCHEMBL30573038	0.80	HTR2C (0.56)	HTR2CSLC6A4HTR2BRXRARXRB
	SCHEMBL31020080	0.80	RXRA (0.57)	HTR2CSLC6A4HTR2BRXRARXRB
	SCHEMBL12167392	0.80	HTR2C (0.56)	HTR2CSLC6A4HTR2BRXRARXRB
	SCHEMBL10801528	0.80	C5AR1 (0.52)	HTR1AADRA1DADRA1AADRA1BC5AR1
	SCHEMBL16433621	0.80	HTR1A (0.50)	MRGPRX4L3MBTL1HTR1AADRA1DADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.