Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNB1 | Q14721 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5731703 | 0.92 | KCNB1 (0.34) | KCNB1MEN1LMNATSHRMAPK1 | |
| SCHEMBL5446830 | 0.86 | MDM2 (0.33) | KCNB1MEN1LMNATSHRMAPK1 | |
| SCHEMBL5446834 | 0.86 | MDM2 (0.33) | KCNB1MEN1LMNATSHRMAPK1 | |
| SCHEMBL5448010 | 0.84 | KCNB1 (0.34) | KCNB1MEN1LMNATSHRMAPK1 | |
| SCHEMBL5448013 | 0.84 | KCNB1 (0.34) | KCNB1MEN1LMNATSHRMAPK1 | |
| SCHEMBL5727980 | 0.82 | KDM4E (0.38) | MEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL5728226 | 0.79 | — | — | |
| SCHEMBL5731959 | 0.78 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL5728575 | 0.77 | GABRA1 (0.33) | — | |
| SCHEMBL6110869 | 0.74 | IKBKB (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694665-A2 | SUBSTITUTED THIOPHENES | AiCuris GmbH & Co. KG (DE) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005063734-A2 | SUBSTITUTED THIOPHENES | AICURIS GMBH & CO. KG (DE) | 2005-07-14 | — | — | WO | disclosed |