Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5728027 | 0.92 | GABRA1 (0.32) | GABRA1GABRG2GABRB3 | |
| SCHEMBL5727459 | 0.84 | POLB (0.36) | — | |
| SCHEMBL5438427 | 0.83 | PLAT (0.37) | GABRA1GABRG2GABRB3 | |
| SCHEMBL5438419 | 0.83 | PLAT (0.37) | GABRA1GABRG2GABRB3 | |
| SCHEMBL5728226 | 0.81 | — | — | |
| SCHEMBL5728467 | 0.81 | ALDH1A1 (0.33) | — | |
| SCHEMBL5727980 | 0.78 | KDM4E (0.38) | — | |
| SCHEMBL5731473 | 0.77 | KCNB1 (0.33) | — | |
| SCHEMBL5728113 | 0.77 | TP53 (0.36) | — | |
| SCHEMBL6110869 | 0.76 | IKBKB (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694665-A2 | SUBSTITUTED THIOPHENES | AiCuris GmbH & Co. KG (DE) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005063734-A2 | SUBSTITUTED THIOPHENES | AICURIS GMBH & CO. KG (DE) | 2005-07-14 | — | — | WO | disclosed |