SCHEMBL57324

SCHEMBL57324

CC(C)(C)c1ccc(O)c(-c2cccc(-c3cccc(-c4cc(C(C)(C)C)ccc4O)n3)n2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
HPGD P15428 1/20 0.50
ALOX15 P16050 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
KMT2A Q03164 4/20 0.46
MEN1 O00255 3/20 0.46
MAPT P10636 2/20 0.46
GAA P10253 2/20 0.46
PKM P14618 1/20 0.46
RECQL P46063 1/20 0.46
HDAC4 P56524 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
NR2F2 P24468 1/20 0.41
CYP2D6 P10635 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
PLA2G1B P04054 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7772549 1.00 ALDH1A1 (0.50) ALDH1A1HPGDALOX15HSD17B10TDP1
Hydrochloric Acid SCHEMBL7234991 0.97 ALDH1A1 (0.47) ALDH1A1HPGDALOX15HSD17B10TDP1
Acetic Acid SCHEMBL7774804 0.90 ALDH1A1 (0.41) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL15674782 0.85 IDH1 (0.43) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL13399048 0.81 ALDH1A1 (0.48) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL25191881 0.80 AR (0.44) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL29785519 0.79 ALDH1A1 (0.70) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL6240718 0.79 ALDH1A1 (0.70) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL11130681 0.79 ALDH1A1 (0.53) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL7232844 0.77 CYP19A1 (0.51) ALDH1A1HPGDALOX15HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3211057-B2 ORGANIC ELECTROLUMINESCENT DEVICES AND METAL COMPLEX COMPOUNDS UDC IRELAND LTD (IE) 2022-11-02 EP disclosed
US-20220344601-A1 Organic Electroluminescent Devices and Metal Complex Compounds UDC IRELAND LTD (IE) 2022-10-27 US disclosed
US-11393989-B2 Organic electroluminescent devices and metal complex compounds UDC IRELAND LIMITED (IE) 2022-07-19 US disclosed
EP-3901235-A1 ORGANIC ELECTROLUMINESCENT DEVICES AND METAL COMPLEX COMPOUNDS UDC Ireland Limited (IE) 2021-10-27 EP disclosed
EP-3623444-B1 ORGANIC ELECTROLUMINESCENT DEVICES AND METAL COMPLEX COMPOUNDS UDC IRELAND LTD (IE) 2021-05-26 EP disclosed
EP-3623444-A1 ORGANIC ELECTROLUMINESCENT DEVICES AND METAL COMPLEX COMPOUNDS UDC Ireland Limited (IE) 2020-03-18 EP disclosed
US-20190355918-A1 Organic Electroluminescent Devices and Metal Complex Compounds UDC IRELAND LTD (IE) 2019-11-21 US disclosed
US-10396299-B2 Organic electroluminescent devices and metal complex compounds UDC IRELAND LIMITED (IE) 2019-08-27 US disclosed
EP-1629063-B2 ORGANIC ELECTROLUMINESCENT DEVICES AND METAL COMPLEX COMPOUNDS UDC IRELAND LTD (IE) 2019-07-17 EP disclosed
US-10153444-B2 Organic electroluminescent devices and metal complex compounds UDC IRELAND LIMITED (IE) 2018-12-11 US disclosed
US-20060222887-A1 Organic electroluminescent device FUJI PHOTO FILM CO., LTD. 2006-10-05 US disclosed
US-20060182992-A1 Platinum complex of 6,6'-bis(2-methoxyphenyl)-2,2'-bipyridyl; complexes having a tridentate- or higher polydentate-chain structure ligand; durability; red, green, blue color purity; short wavelength; excellent in both luminous characteristics; displays; brightness; light sources UDC IRELAND LIMITED (IE) 2006-08-17 US disclosed
US-20060141285-A1 Organic electroluminescent device FUJI PHOTO FILM CO., LTD. 2006-06-29 US disclosed
US-20060105202-A1 Organic electroluminescent device FUJI PHOTO FILM CO., LTD. 2006-05-18 US disclosed
US-20060099450-A1 Organic electroluminescent device FUJI PHOTO FILM CO., LTD. 2006-05-11 US disclosed
US-20060099451-A1 Organic electroluminescent device FUJI PHOTO FILM CO., LTD. 2006-05-11 US disclosed
US-6541490-B1 Treating ischemia or reoxygenation injury; preparation from a bipyridine, a benzeneboronic acid and a manganese salt EUKARION, INC. 2003-04-01 US disclosed
EP-1119573-A2 BIPYRIDINE MANGANESE COMPLEXES EUKARION, INC. (US) 2001-08-01 EP disclosed
US-6177419-B1 ANTIOXIDANT CHELATE COMPOUNDS FOR PREVENTING OXYGEN FREE RADICAL-ASSOCIATED DISEASES IN MAMMALS; NEUROPROTECTANTS, SUPEROXIDE DISMUTASE (SOD), CATALASE (CAT) AND/OR PEROXIDASE (POD) MIMETICS EUKARION, INC. 2001-01-23 US disclosed
WO-2000009512-A2 BIPYRIDINE MANGANESE COMPLEXES EUKARION, INC. (US) 2000-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10153444-B2 Organic electroluminescent devices and metal complex compounds EPCAM, TPR, L1CAM ALDH1A1 2524/4885HPGD 4640/4885ALOX15 3479/4885
US-20220344601-A1 Organic Electroluminescent Devices and Metal Complex Compounds EPCAM, TPR, L1CAM ALDH1A1 2524/4885HPGD 4640/4885ALOX15 3479/4885
US-20190355918-A1 Organic Electroluminescent Devices and Metal Complex Compounds EPCAM, TPR, L1CAM ALDH1A1 2524/4885HPGD 4640/4885ALOX15 3479/4885
US-10396299-B2 Organic electroluminescent devices and metal complex compounds EPCAM, TPR, L1CAM ALDH1A1 2524/4885HPGD 4640/4885ALOX15 3479/4885
US-11393989-B2 Organic electroluminescent devices and metal complex compounds EPCAM, TPR, L1CAM ALDH1A1 2524/4885HPGD 4640/4885ALOX15 3479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.