Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2324355 | 0.77 | HSD11B1 (0.57) | KIF11HSD11B1 | |
| SCHEMBL19965674 | 0.76 | KIF11 (0.55) | KIF11CYP2A6CYP19A1EPHX2ABCC9 | |
| SCHEMBL30526000 | 0.76 | KIF11 (0.55) | KIF11CYP2A6CYP19A1EPHX2ABCC9 | |
| SCHEMBL3434654 | 0.76 | KIF11 (0.55) | KIF11CYP2A6CYP19A1EPHX2ABCC9 | |
| SCHEMBL13845191 | 0.76 | KIF11 (0.59) | KIF11CYP2A6CYP19A1EPHX2HSD11B1 | |
| SCHEMBL379565 | 0.76 | KIF11 (0.59) | KIF11CYP2A6CYP19A1EPHX2ALDH1A1 | |
| SCHEMBL1099894 | 0.74 | KIF11 (0.57) | KIF11CYP2A6CYP19A1EPHX2ALDH1A1 | |
| SCHEMBL13891047 | 0.73 | KIF11 (0.52) | KIF11CYP2A6CYP19A1EPHX2MLYCD | |
| SCHEMBL6496377 | 0.73 | KIF11 (0.52) | KIF11CYP2A6CYP19A1EPHX2MLYCD | |
| SCHEMBL30800873 | 0.73 | KIF11 (0.52) | KIF11CYP2A6CYP19A1EPHX2ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720836-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO [D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005082859-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2005-09-09 | — | — | WO | disclosed |