Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 11/20 | 0.42 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 8/20 | 0.41 |
| ▸ | AKT1 | P31749 | 4/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5732650 | 0.90 | ADRB2 (0.43) | ADRB2TDP1KCNH2 | |
| SCHEMBL5742293 | 0.89 | PIK3CG (0.48) | PIK3CAMTORAKT1PIK3CGKCNH2 | |
| SCHEMBL5733902 | 0.86 | ADRB2 (0.44) | PIK3CAADRB2MTORTDP1 | |
| SCHEMBL5732823 | 0.86 | ADRB2 (0.42) | ADRB2MTORPIK3CDTDP1KCNH2 | |
| SCHEMBL5732806 | 0.85 | ADRB2 (0.43) | ADRB2TDP1KCNH2 | |
| SCHEMBL5744355 | 0.84 | ADRB2 (0.42) | ADRB2TDP1KCNH2 | |
| SCHEMBL5734622 | 0.84 | TOP2A (0.46) | ADRB2TDP1KCNH2 | |
| SCHEMBL7691311 | 0.83 | TOP2A (0.49) | ADRB2TDP1 | |
| SCHEMBL5733232 | 0.83 | TOP2A (0.48) | ADRB2TDP1 | |
| SCHEMBL5733609 | 0.83 | ADRB2 (0.44) | ADRB2TDP1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070713-B1 | QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2006-10-18 | — | — | EP | disclosed |
| US-6335447-B1 | BACTERICIDES | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-01-01 | — | — | US | disclosed |
| EP-1070713-A1 | QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2001-01-24 | — | — | EP | disclosed |