Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.49 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5734622 | 0.89 | TOP2A (0.46) | TOP2ATOP2BTDP1ADRB2ELANE | |
| SCHEMBL5733609 | 0.88 | ADRB2 (0.44) | TOP2ATOP2BTDP1ADRB2ELANE | |
| SCHEMBL5732650 | 0.88 | ADRB2 (0.43) | TOP2ATOP2BRAB9ANPC1TDP1 | |
| SCHEMBL5732731 | 0.87 | TOP2A (0.62) | TOP2ATOP2BKDM4EHTT | |
| SCHEMBL5733232 | 0.85 | TOP2A (0.48) | TOP2ATOP2BTDP1ADRB2MEN1 | |
| SCHEMBL5732607 | 0.83 | PIK3CA (0.42) | TDP1ADRB2 | |
| SCHEMBL5732806 | 0.83 | ADRB2 (0.43) | TOP2ATOP2BTDP1ADRB2ELANE | |
| SCHEMBL5732980 | 0.83 | ADRB2 (0.41) | TOP2ATOP2BTDP1ADRB2ELANE | |
| SCHEMBL5733902 | 0.83 | ADRB2 (0.44) | TOP2ATOP2BTDP1ADRB2ELANE | |
| SCHEMBL5733321 | 0.82 | ADRB2 (0.45) | TOP2ATOP2BTDP1ADRB2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6335447-B1 | BACTERICIDES | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-01-01 | — | — | US | disclosed |
| EP-1070713-A1 | QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2001-01-24 | — | — | EP | disclosed |