SCHEMBL5732640

SCHEMBL5732640

CC(C)(C)OB(OC(C)(C)C)OC(C)(C)C.[KH]

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL196117 0.96 ALDH1A1 (0.36) ALDH1A1TSHRTDP1
Fluoride SCHEMBL15367056 0.92 ALDH1A1 (0.33) ALDH1A1TSHRTDP1
SCHEMBL2078957 0.92 ALDH1A1 (0.33) ALDH1A1TSHRTDP1
SCHEMBL9387756 0.92 ALDH1A1 (0.33) ALDH1A1TSHRTDP1
SCHEMBL7145095 0.92 ALDH1A1 (0.33) ALDH1A1TSHRTDP1
Lithium Ion SCHEMBL8992466 0.88 TSHR (0.31) ALDH1A1TSHRTDP1
SCHEMBL27790915 0.77 ALDH1A1 (0.38) ALDH1A1
SCHEMBL2912820 0.77 ALDH1A1 (0.32) ALDH1A1
SCHEMBL5597696 0.72 TSHR (0.41) TSHRTDP1
SCHEMBL12675478 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0901996-B1 PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINES MITSUI CHEMICALS INC (JP) 2006-02-01 EP disclosed
US-6222072-B1 RACTING IMINE WITH HYDRIDE REAGENT IN PRESENCE OF OPTICALLY ACTIVE METAL COMPOUND, WHEREIN HYDRIDE REAGENT IS A METAL HYDRIDE, REAGENT THAT UNDERGOES METAL EXCHANGE, METAL TRIALKOXY HYDRIDE COMPLEX OR METAL(TRICARBOXYLIC ACID)HYDRIDE MITSUI CHEMICALS INC. (JP) 2001-04-24 US disclosed
EP-0901996-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINES Mitsui Chemicals, Inc. (JP) 1999-03-17 EP disclosed