Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 8/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 8/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5733232 | 0.93 | TOP2A (0.48) | ADRB2TOP2ATOP2BTDP1MEN1 | |
| SCHEMBL5732622 | 0.92 | ADRB2 (0.41) | ADRB2TOP2ATOP2BTDP1MEN1 | |
| SCHEMBL5734282 | 0.89 | TOP2A (0.53) | TOP2ATOP2BKCNH2 | |
| SCHEMBL5732797 | 0.88 | TOP2A (0.40) | ADRB2TOP2ATOP2BTDP1MEN1 | |
| SCHEMBL5734622 | 0.84 | TOP2A (0.46) | ADRB2TOP2ATOP2BTDP1MAPK1 | |
| SCHEMBL5733321 | 0.83 | ADRB2 (0.45) | ADRB2TOP2ATOP2BTDP1MEN1 | |
| SCHEMBL5732650 | 0.83 | ADRB2 (0.43) | ADRB2TOP2ATOP2BTDP1MEN1 | |
| SCHEMBL9720466 | 0.82 | TOP2A (0.45) | ADRB2TOP2ATOP2BKMT2AALDH1A1 | |
| SCHEMBL5733533 | 0.81 | TOP2A (0.52) | TOP2ATOP2BKCNH2 | |
| SCHEMBL5733609 | 0.81 | ADRB2 (0.44) | ADRB2TOP2ATOP2BTDP1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070713-B1 | QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2006-10-18 | — | — | EP | disclosed |
| US-6335447-B1 | BACTERICIDES | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-01-01 | — | — | US | disclosed |
| EP-1070713-A1 | QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2001-01-24 | — | — | EP | disclosed |