Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 14/20 | 0.53 |
| ▸ | TOP2B | Q02880 | 14/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5733533 | 0.92 | TOP2A (0.52) | TOP2ATOP2BKCNH2GSK3B | |
| SCHEMBL5732781 | 0.91 | TOP2A (0.62) | TOP2ATOP2BKCNH2 | |
| Hydrochloric Acid SCHEMBL5733325 | 0.91 | TOP2A (0.52) | TOP2ATOP2BKCNH2GSK3B | |
| SCHEMBL5733103 | 0.89 | ADRB2 (0.42) | TOP2ATOP2BKCNH2 | |
| SCHEMBL5732660 | 0.82 | TOP2A (0.60) | TOP2ATOP2BKCNH2GSK3B | |
| SCHEMBL5732622 | 0.81 | ADRB2 (0.41) | TOP2ATOP2BKCNH2 | |
| SCHEMBL5734038 | 0.81 | TOP2A (0.47) | TOP2ATOP2BKCNH2GSK3B | |
| SCHEMBL5733232 | 0.81 | TOP2A (0.48) | TOP2ATOP2B | |
| SCHEMBL9720558 | 0.80 | TOP2A (0.57) | TOP2ATOP2B | |
| SCHEMBL5742552 | 0.80 | TOP2A (0.45) | TOP2ATOP2BKCNH2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070713-B1 | QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2006-10-18 | — | — | EP | disclosed |
| US-6335447-B1 | BACTERICIDES | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-01-01 | — | — | US | disclosed |
| EP-1070713-A1 | QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2001-01-24 | — | — | EP | disclosed |