Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 4/20 | 0.46 |
| ▸ | TGM2 | P21980 | 12/20 | 0.46 |
| ▸ | F13A1 | P00488 | 9/20 | 0.46 |
| ▸ | TGM1 | P22735 | 6/20 | 0.46 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5733782 | 0.84 | TGM2 (0.47) | TGM2F13A1TGM1TGM3 | |
| Hydrochloric Acid SCHEMBL5736580 | 0.82 | CNR1 (0.45) | STSTGM2 | |
| Hydrochloric Acid SCHEMBL5736583 | 0.82 | CNR1 (0.45) | STSTGM2 | |
| SCHEMBL5734380 | 0.81 | TGM2 (0.48) | STSTGM2F13A1TGM1TGM3 | |
| SCHEMBL5734167 | 0.81 | TGM2 (0.48) | STSTGM2F13A1TGM1TGM3 | |
| SCHEMBL28919020 | 0.78 | STS (0.63) | STSTGM2F13A1TGM1TGM3 | |
| SCHEMBL13239816 | 0.75 | TGM2 (0.59) | STSTGM2F13A1TGM1TGM3 | |
| SCHEMBL5253160 | 0.73 | POLB (0.70) | STSTGM2F13A1TGM1POLB | |
| SCHEMBL2252120 | 0.72 | TGM2 (0.63) | TGM2F13A1TGM1 | |
| SCHEMBL3248533 | 0.71 | TGM2 (0.55) | STSTGM2F13A1TGM1TGM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986551-B1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL (JP) | 2006-08-02 | — | — | EP | disclosed |
| US-6359134-B1 | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-0986551-A1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Pharmaceutical Company Limited (JP) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998054164-A1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-03 | — | — | WO | disclosed |