SCHEMBL573380

SCHEMBL573380

C=C(C)c1ccc(OCC2CCC3OC3C2)cc1

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ PARP15 Q460N3 4/20 0.44
▸ PARP10 Q53GL7 4/20 0.44
▸ PARP2 Q9UGN5 2/20 0.44
▸ NR1H4 Q96RI1 1/20 0.37
▸ DRD2 P14416 1/20 0.36
▸ DRD4 P21917 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5819818 0.84 KDM4E (0.40) PARP15PARP10PARP2
SCHEMBL12227198 0.84 PARP15 (0.60) PARP15PARP10PARP2NR1H4
SCHEMBL12227196 0.81 PARP15 (0.55) PARP15PARP10PARP2
SCHEMBL14817248 0.81 PARP15 (0.43) PARP15PARP10PARP2
SCHEMBL19901450 0.79 HRH3 (0.43) PARP15PARP10PARP2
SCHEMBL5749654 0.78 DRD2 (0.48) DRD2DRD4
SCHEMBL572868 0.78 CHRNB2 (0.39) PARP15PARP10PARP2DRD2DRD4
SCHEMBL14817284 0.78 PARP15 (0.40) PARP15PARP10PARP2
SCHEMBL12787696 0.78 MAPT (0.46) PARP15PARP10PARP2DRD2DRD4
SCHEMBL12730750 0.77 PARP15 (0.39) PARP15PARP10PARP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9040630-B2 Graft copolymers of polyfarnesenes with condensation polymers Amyris, Inc. (US) 2015-05-26 — — US claimed
EP-2601229-B1 GRAFT COPOLYMERS OF POLYFARNESENES WITH CONDENSATION POLYMERS AMYRIS INC (US) 2013-10-16 — — EP claimed
EP-2601229-A1 GRAFT COPOLYMERS OF POLYFARNESENES WITH CONDENSATION POLYMERS Amyris, Inc. (US) 2013-06-12 — — EP claimed
US-20130123379-A1 GRAFT COPOLYMERS OF POLYFARNESENES WITH CONDENSATION POLYMERS Amyris, Inc. (US) 2013-05-16 — — US claimed
WO-2012018682-A1 GRAFT COPOLYMERS OF POLYFARNESENES WITH CONDENSATION POLYMERS Amyris, Inc. (US) 2012-02-09 — — WO claimed
EP-2817342-B1 POLYMERIZATION OF COMPOSITIONS COMPRISING A FARNESENE AMYRIS INC (US) 2016-05-25 — — EP disclosed
US-9040630-B2 Graft copolymers of polyfarnesenes with condensation polymers Amyris, Inc. (US) 2015-05-26 — — US disclosed
US-20150025193-A1 POLYMERIZATION OF COMPOSITIONS COMPRISING A FARNESENE Amyris, Inc. (US) 2015-01-22 — — US disclosed
EP-2817342-A1 POLYMERIZATION OF COMPOSITIONS COMPRISING A FARNESENE Amyris, Inc. (US) 2014-12-31 — — EP disclosed
US-8592543-B2 Polyfarnesenes EUAGORE, LLC 2013-11-26 — — US disclosed
EP-2601229-B1 GRAFT COPOLYMERS OF POLYFARNESENES WITH CONDENSATION POLYMERS AMYRIS INC (US) 2013-10-16 — — EP disclosed
WO-2013126129-A1 POLYMERIZATION OF COMPOSITIONS COMPRISING A FARNESENE Amyris, Inc. (US) 2013-08-29 — — WO disclosed
EP-2601229-A1 GRAFT COPOLYMERS OF POLYFARNESENES WITH CONDENSATION POLYMERS Amyris, Inc. (US) 2013-06-12 — — EP disclosed
US-20130123379-A1 GRAFT COPOLYMERS OF POLYFARNESENES WITH CONDENSATION POLYMERS Amyris, Inc. (US) 2013-05-16 — — US disclosed
US-20120165474-A1 POLYFARNESENES Amyris, Inc. (US) 2012-06-28 — — US disclosed
WO-2012018682-A1 GRAFT COPOLYMERS OF POLYFARNESENES WITH CONDENSATION POLYMERS Amyris, Inc. (US) 2012-02-09 — — WO disclosed
EP-0805186-B1 THERMOSETTING COMPOSITION, METHOD OF FINISH COATING, AND COATED ARTICLES NOF CORP (JP) 2002-05-29 — — EP disclosed
US-6242046-B1 BLEND OF POLYMER, METAL OXIDE, SOLVENT AND WATER BASF NOF COATINGS COMPANY, LIMITED (JP) 2001-06-05 — — US disclosed
US-6103387-A THERMOSETTING RESIN COMPRISING A CERAMIC, WHICH GIVES A CURED PRODUCT HAVING EXCELLENT STAIN RESISTANCE, STAIN-REMOVING PROPERTY, WEATHERING RESISTANCE, LIGHT RESISTANCE, CHEMICAL RESISTANCE, MOISTURE RESISTANCE AND APPEARANCE NOF CORPORATION (JP) 2000-08-15 — — US disclosed
EP-0805186-A1 THERMOSETTING COMPOSITION, METHOD OF FINISH COATING, AND COATED ARTICLES NOF CORPORATION (JP) 1997-11-05 — — EP disclosed
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