SCHEMBL5734

SCHEMBL5734

Cc1cccc([N+](=O)[O-])c1F

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
HSD17B10 Q99714 1/20 0.63
TDP1 Q9NUW8 5/20 0.59
L3MBTL1 Q9Y468 2/20 0.55
ALDH1A1 P00352 5/20 0.54
GPR35 Q9HC97 2/20 0.48
NPC1 O15118 1/20 0.43
MAPT P10636 1/20 0.43
MAPK1 P28482 1/20 0.43
LMNA P02545 1/20 0.43
S100A4 P26447 1/20 0.42
MGAM O43451 1/20 0.42
GAA P10253 1/20 0.42
SI P14410 1/20 0.42
MGAM2 Q2M2H8 1/20 0.42
KCNMA1 Q12791 1/20 0.42
CYP3A4 P08684 1/20 0.41
RECQL P46063 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29480852 1.00 TSHR (0.64) TSHRSMN1; SMN2HSD17B10TDP1L3MBTL1
SCHEMBL31257672 0.86 TSHR (0.53) TSHRSMN1; SMN2HSD17B10TDP1L3MBTL1
SCHEMBL3010961 0.84 TDP1 (0.61) TSHRSMN1; SMN2HSD17B10TDP1ALDH1A1
Ammonia Solution, Strong SCHEMBL28763100 0.82 TDP1 (0.58) TSHRSMN1; SMN2HSD17B10TDP1ALDH1A1
SCHEMBL29740027 0.81 HSD17B10 (0.48) TSHRSMN1; SMN2HSD17B10TDP1L3MBTL1
SCHEMBL3391686 0.81 HSD17B10 (0.48) TSHRSMN1; SMN2HSD17B10TDP1L3MBTL1
SCHEMBL307855 0.78 TDP1 (0.54) TSHRSMN1; SMN2HSD17B10TDP1L3MBTL1
SCHEMBL29538967 0.78 TSHR (1.00) TSHRSMN1; SMN2HSD17B10TDP1L3MBTL1
SCHEMBL6051840 0.78 TSHR (0.69) TSHRSMN1; SMN2HSD17B10TDP1L3MBTL1
SCHEMBL29355089 0.78 TDP1 (0.54) TSHRSMN1; SMN2HSD17B10TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 511 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121574054-B Preparation method of 2-fluoro-3-nitrobenzoic acid 济南国鼎医药科技有限公司 2026-05-15 CN claimed
US-12583821-B2 Salt of omecamtiv mecarbil and process for preparing salt CYTOKINETICS, INC. (US) 2026-03-24 US claimed
CN-121574054-A Preparation method of 2-fluoro-3-nitrobenzoic acid 济南国鼎医药科技有限公司 2026-02-27 CN claimed
US-20250179005-A1 CRYSTALLINE 2-FLUORO-3-NITROTOLUENE AND PROCESS FOR THE PREPARATION THEREOF AMGEN INC. 2025-06-05 US claimed
CN-112654602-B Crystalline 2-fluoro-3-nitrotoluene and process for preparing the same 意大利合成制造有限公司 2025-05-16 CN claimed
CN-114560774-B Synthesis method of 2-fluoro-3-nitrobenzoic acid 九洲药业(杭州)有限公司 2025-05-06 CN claimed
CN-119775143-A Synthesis method of 2-fluoro-3-nitrobenzoic acid 河北科技大学 2025-04-08 CN claimed
US-12162815-B2 Crystalline 2-fluoro-3-nitrotoluene and process for the preparation thereof F.I.S.—Fabbrica Italiana Sintetici S.p.A. (IT) 2024-12-10 US claimed
EP-4305018-A2 SYNTHESIS OF OMECAMTIV MECARBIL Amgen Inc. (US) 2024-01-17 EP claimed
CN-117157274-A Synthesis of olmesartan Mo Kabi mol 安进股份有限公司 2023-12-01 CN claimed
EP-3477758-A1 NONAQUEOUS ELECTROLYTE, POWER STORAGE ELEMENT, AND METHOD FOR PRODUCING POWER STORAGE ELEMENT GS Yuasa International Ltd. (JP) 2019-05-01 EP claimed
WO-2019006231-A1 SYNTHESIS OF OMECAMTIV MECARBIL AMGEN INC. (US) 2019-01-03 WO claimed
US-7651885-B2 Electronic device fabrication process XEROX CORPORATION (US) 2010-01-26 US claimed
US-7539006-B2 Electrolytic solution for driving electrolytic capacitor and electrolytic capacitor RUBYCON CORPORATION (JP) 2009-05-26 US claimed
CN-101177400-A Method for producing 2-fluorin-3-nitrotoluene LU TIEHUAN (CN) 2008-05-14 CN claimed
US-20070141747-A1 Electronic device fabrication process XEROX CORPORATION 2007-06-21 US claimed
US-20070029529-A1 Electrolytic solution for driving electrolytic capacitor and electrolytic capacitor KOMATSU AKIHIKO 2007-02-08 US claimed
US-20040245105-A1 Electrolyte solution for driving electrolytic capacitor and electrolytic capacitor RUBYCON CORPORATION (JP) 2004-12-09 US claimed
EP-1437749-A1 ELECTROLYTE SOLUTION FOR DRIVING ELECTROLYTIC CAPACITOR AND ELECTROLYTIC CAPACITOR Rubycon Corporation (JP) 2004-07-14 EP claimed
US-4502995-A Nucleophilic substitution process ETHYL CORPORATION (US) 1985-03-05 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250179005-A1 CRYSTALLINE 2-FLUORO-3-NITROTOLUENE AND PROCESS FOR THE PREPARATION THEREOF NOX5, NOX3, NOS2 TSHR 4003/4885SMN1; SMN2 2663/4885HSD17B10 454/4885
US-12162815-B2 Crystalline 2-fluoro-3-nitrotoluene and process for the preparation thereof NOX3, NOX5, NOS2 TSHR 4074/4885SMN1; SMN2 2679/4885HSD17B10 477/4885
US-12583821-B2 Salt of omecamtiv mecarbil and process for preparing salt SLC28A2, SLC28A1, SLC5A11 TSHR 2392/4885SMN1; SMN2 1614/4885HSD17B10 4042/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.