Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.93 |
| ▸ | DAO | P14920 | 1/20 | 0.93 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.93 |
| ▸ | CES2 | O00748 | 3/20 | 0.74 |
| ▸ | CES1 | P23141 | 3/20 | 0.74 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.74 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA3 | P07451 | 2/20 | 0.55 |
| ▸ | CA4 | P22748 | 2/20 | 0.55 |
| ▸ | CA6 | P23280 | 2/20 | 0.55 |
| ▸ | CA5A | P35218 | 2/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL14830225 | 1.00 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL8193928 | 1.00 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL8109849 | 1.00 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL27756980 | 1.00 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL1900827 | 1.00 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL27604381 | 1.00 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL1681473 | 1.00 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL27687929 | 1.00 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL841157 | 0.97 | TSHR (0.88) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL5672398 | 0.97 | TSHR (0.88) | TSHRDAONAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 366 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122060155-A | Demulsifier for raw gas quenching oil emulsion and preparation method and application thereof | 山西东义煤电铝集团煤化工有限公司 | 2026-05-19 | — | — | CN | claimed |
| WO-2023187786-A1 | EXTERIOR CLADDING SYSTEM AND EXTERIOR WALLS COMPRISING THERAMLLY INSULATING MINERAL FOAM | Termokir Industries (1980) Ltd (IL) | 2023-10-05 | — | — | WO | claimed |
| CN-116621910-A | Artificial potassium ion transporter with anti-hepatic fibrosis activity and preparation method and application thereof | 厦门大学 | 2023-08-22 | — | — | CN | claimed |
| EP-3237353-B1 | METHOD FOR THE CONTINUOUS PRODUCTION OF A LOW-DENSITY MINERAL FOAM | HOLCIM TECHNOLOGY LTD (CH) | 2022-04-20 | — | — | EP | claimed |
| CN-111773225-A | KRAS and its mutant expression inhibitor | 山东轩竹医药科技有限公司 | 2020-10-16 | — | — | CN | claimed |
| CN-111777620-A | Novel use of tyrosine kinase inhibitor | 山东轩竹医药科技有限公司 | 2020-10-16 | — | — | CN | claimed |
| WO-2019110795-A1 | OXIDATION OF A PYRAZOLYL KETONE COMPOUND TO THE CORRESPONDING CARBOXYLIC ACID | SOLVAY SA (BE) | 2019-06-13 | — | — | WO | claimed |
| EP-3495351-A1 | OXIDATION OF A PYRAZOLYL KETONE COMPOUND TO THE CORRESPONDING CARBOXYLIC ACID | SOLVAY SA (BE) | 2019-06-12 | — | — | EP | claimed |
| EP-2822913-B1 | CONTINUOUS METHOD FOR MANUFACTURING A MATERIAL WHICH CONTAINS A HYDRAULIC BINDER AND WHICH IS LIGHTENED BY EXPANSION | SAINT GOBAIN WEBER (FR) | 2018-09-05 | — | — | EP | claimed |
| US-20170349498-A1 | METHOD FOR THE CONTINUOUS PRODUCTION OF A LOW-DENSITY MINERAL FOAM | AMRIZE TECHNOLOGY SWITZERLAND LLC (CH) | 2017-12-07 | — | — | US | claimed |
| WO-2006102138-A1 | FLAME RETARDANTS AND FLAME RETARDED POLYMERS | GREAT LAKES CHEMICAL CORPORATION (US) | 2006-09-28 | — | — | WO | claimed |
| US-7038061-B2 | Crystalline anhydrous and monohydrate benzoate salts of (2′S,3S)-3-hydroxy-N-(2-[N-methyl-N-4-(N-propylamino-carbonyl)phenyl]amino-2-phenyl)-ethylpyrrolidine | PFIZER INC (US) | 2006-05-02 | — | — | US | claimed |
| US-6835374-B2 | Fine particle size; mixing, suspension active material with surfactant | REHEIS, INC. | 2004-12-28 | — | — | US | claimed |
| US-20040235936-A1 | Crystalline anhydrous and monohydrate benzoate salts of (2'S,3S)-3-hydroxy-N-{2-[N-methyl-N-4-(N-propylamino-carbonyl)phenyl]amino-2-phenyl}-ethylpyrrolidine | PFIZER INC. | 2004-11-25 | — | — | US | claimed |
| EP-1478622-A1 | CRYSTALLINE ANHYDROUS AND MONOHYDRATE BENZOATE SALTS OF (2'S,3S)-3-HYDROXY-N- 2 N-METHYL-N-4-(N-PROPYLAMINO-CARBONYL)PHENYL]AMINO-2-PHENYL -ETHYLPYRROLIDINE | Pfizer Products Inc. (US) | 2004-11-24 | — | — | EP | claimed |
| EP-1417953-A2 | Novel antiperspirant/deodorant active for no white residue sticks and soft solids | REHEIS, INC. (US) | 2004-05-12 | — | — | EP | claimed |
| US-20040081632-A1 | Novel antiperspirant/deodorant active for no white residue sticks and soft solids | SUMMIT RESEARCH LABS, INC. | 2004-04-29 | — | — | US | claimed |
| WO-2003072544-A1 | CRYSTALLINE ANHYDROUS AND MONOHYDRATE BENZOATE SALTS OF (2'S,3S)-3-HYDROXY-N-{2{N-METHYL-N-4-(N-PROPYLAMINO-CARBONYL)PHENYL]AMINO-2-PHENYL}-ETHYLPYRROLIDINE | PFIZER PRODUCTS INC. (US) | 2003-09-04 | — | — | WO | claimed |
| EP-0045982-B1 | PROCESS FOR THE PREPARATION OF ARYLTHALLIUMCARBOXYLATE PERCHLORATES; 2-CARBONYLOXIPHENYLTHALLIUM(III) PERCHLORATE, PREPARATION THEREOF AND ITS ULTERIOR TREATMENT | RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1984-02-15 | — | — | EP | claimed |
| US-4306933-A | Tin/tin-lead stripping solutions | CHEMLINE INDUSTRIES (US) | 1981-12-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235936-A1 | Crystalline anhydrous and monohydrate benzoate salts of (2'S,3S)-3-hydroxy-N-{2-[N-methyl-N-4-(N-propylamino-carbonyl)phenyl]amino-2-phenyl}-ethylpyrrolidine | HCAR2, NOD2, NOD1 | TSHR 1386/4885DAO 1960/4885NAPRT 1277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.