Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 12/20 | 0.48 |
| ▸ | F2 | P00734 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5736839 | 0.90 | F10 (0.51) | SMN1; SMN2LMNAF10F2ATM | |
| SCHEMBL5737352 | 0.89 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNAL3MBTL1F10F2 | |
| SCHEMBL6729737 | 0.81 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNAL3MBTL1F10F2 | |
| SCHEMBL5735417 | 0.79 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNAF10ATMPOLB | |
| SCHEMBL5734070 | 0.79 | SMN1; SMN2 (0.66) | SMN1; SMN2LMNAL3MBTL1F10ATM | |
| SCHEMBL5734359 | 0.79 | F10 (0.54) | SMN1; SMN2LMNAF10F2ATM | |
| Hydrochloric Acid SCHEMBL6195882 | 0.79 | SMN1; SMN2 (0.64) | SMN1; SMN2LMNAL3MBTL1F10ATM | |
| SCHEMBL6305998 | 0.77 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNAL3MBTL1F10F2 | |
| SCHEMBL5735028 | 0.76 | LMNA (0.53) | SMN1; SMN2LMNAL3MBTL1F10F2 | |
| SCHEMBL5734273 | 0.76 | F10 (0.50) | SMN1; SMN2LMNAF10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986551-B1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL (JP) | 2006-08-02 | — | — | EP | disclosed |
| US-6359134-B1 | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-0986551-A1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Pharmaceutical Company Limited (JP) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998054164-A1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-03 | — | — | WO | disclosed |