SCHEMBL5734698

SCHEMBL5734698

Nc1ccc(S(=O)(=O)O)cc1F

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.68
CA2 P00918 3/20 0.68
CA9 Q16790 2/20 0.68
CA12 O43570 2/20 0.68
CA7 P43166 2/20 0.68
CA14 Q9ULX7 2/20 0.68
CA4 P22748 1/20 0.68
CA6 P23280 1/20 0.68
CA5A P35218 1/20 0.68
CA5B Q9Y2D0 1/20 0.68
ALDH1A1 P00352 6/20 0.57
HSD17B10 Q99714 3/20 0.57
NT5E P21589 3/20 0.50
CASP6 P55212 3/20 0.50
TSHR P16473 2/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
TDP1 Q9NUW8 1/20 0.48
GAA P10253 3/20 0.47
KDM4E B2RXH2 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14471903 0.83 ALDH1A1 (0.62) CA1CA2CA9CA12CA7
SCHEMBL3072708 0.83 HSD17B10 (0.51) CA1CA2CA9CA12CA7
SCHEMBL2807669 0.83 CA1 (0.73) CA1CA2CA9CA12CA7
SCHEMBL30291161 0.81 CA2 (1.00) CA1CA2CA9CA12CA7
SCHEMBL1179872 0.81 CA2 (1.00) CA1CA2CA9CA12CA7
SCHEMBL31618973 0.81 CA1 (0.70) CA1CA2CA9CA12CA7
SCHEMBL1979458 0.80 TDP1 (0.48) CA1CA2CA9CA12CA7
SCHEMBL391971 0.80 ALDH1A1 (0.69) CA1CA2CA9CA12CA7
SCHEMBL2778156 0.79 CA1 (0.68) CA1CA2CA9CA12CA7
SCHEMBL221279 0.79 CA1 (0.68) CA1CA2CA9CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024221045-A1 IMMUNOGENIC COMPOSITION GRIFFITH UNIVERSITY (AU) 2024-10-31 WO disclosed
EP-3581617-A1 COMPOSITIONS COMPRISING A FILM-FORMING POLYMER AND AN AROMATIC ACID OR SALT THEREOF, AND PREPARATION AND USES THEREOF Synthomer (UK) Ltd. (GB) 2019-12-18 EP disclosed
EP-1064274-B1 BENZENESULFONAMIDE DERIVATIVES AND THEIR USE AS MEDICAMENTS ASTRAZENECA AB (SE) 2006-04-19 EP disclosed
WO-2004049914-A2 METHODS FOR REACTING AN ANTIGEN MASKING COMPOUND WITH RED BLOOD CELLS WITH HIGH EFFICIENCY CERUS CORPORATION (US) 2004-06-17 WO disclosed
WO-2004050897-A2 METHODS FOR PREPARING ANTIGEN MASKED RED BLOOD CELLS HAVING REDUCED HEMOLYSIS BY SERA CERUS CORPORATION (US) 2004-06-17 WO disclosed
WO-2004050848-A2 METHODS FOR ANTIGEN MASKING OF RED BLOOD CELLS RESULTING IN REDUCED HEMOLYSIS CERUS CORPORATION (US) 2004-06-17 WO disclosed
US-6667342-B1 Elevation of pyruvate dehydrogenase activity ASTRAZENECA AB (SE) 2003-12-23 US disclosed
US-20030207247-A1 Preparation of red blood cells having reduced immunogenicity CERUS CORPORATION (US) 2003-11-06 US disclosed
WO-2003047650-A2 PREPARATION OF RED BLOOD CELLS HAVING REDUCED IMMUNOGENICITY CERUS CORPORATION (US) 2003-06-12 WO disclosed
EP-1284743-A2 PREPARATION OF A PATHOGEN INACTIVATED SOLUTION OF RED BLOOD CELLS HAVING REDUCED IMMUNOGENICITY Cerus Corporation (US) 2003-02-26 EP disclosed
WO-2001091775-A2 PREPARATION OF A PATHOGEN INACTIVATED SOLUTION OF RED BLOOD CELLS HAVING REDUCED IMMUNOGENICITY CERUS CORPORATION (US) 2001-12-06 WO disclosed
CN-1293666-A Phenylthioamide derivatives and their use as pharmaceuticals ASTRA ZENECA LTD (SE) 2001-05-02 CN disclosed
EP-0921817-B1 PEGYLATION PROCESS POLYMASC PHARMACEUTICALS PLC (GB) 2001-03-28 EP disclosed
EP-1064274-A1 BENZENESULFONAMIDE DERIVATIVES AND THEIR USE AS MEDICAMENTS AstraZeneca AB (SE) 2001-01-03 EP disclosed
WO-1999047508-A1 BENZENESULFONAMIDE-DERIVATIVES AND THEIR USE AS MEDICAMENTS ASTRAZENECA AB (SE) 1999-09-23 WO disclosed
EP-0921817-A1 PEGYLATION PROCESS PolyMASC Pharmaceuticals plc (GB) 1999-06-16 EP disclosed
WO-1998032466-A1 PEGYLATION PROCESS POLYMASC PHARMACEUTICALS PLC (GB) 1998-07-30 WO disclosed
US-4801693-A DYEING WOOL, CELLULOSE, OR COTTON BASF AKTIENGESELLSCHAFT (DE) 1989-01-31 US disclosed
EP-0167785-B1 REACTIVE DYES BASF Aktiengesellschaft (DE) 1988-08-03 EP disclosed
EP-0167785-A1 Reactive dyes BASF Aktiengesellschaft (DE) 1986-01-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030207247-A1 Preparation of red blood cells having reduced immunogenicity CD47, HLA-C, HLA-B CA1 489/4885CA2 1519/4885CA9 1429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.