Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6578320 | 0.86 | SMN1; SMN2 (0.42) | KMT2AMEN1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL5736873 | 0.83 | HTT (0.40) | KMT2AMEN1SMN1; SMN2TSHRMAPT | |
| SCHEMBL6580916 | 0.76 | RAB9A (0.43) | KMT2AMEN1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL9832996 | 0.75 | HTR2B (0.46) | SMN1; SMN2ALDH1A1MAPTGAANPC1 | |
| SCHEMBL19469567 | 0.74 | SMN1; SMN2 (0.47) | KMT2AMEN1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL11455838 | 0.73 | HTR2B (0.48) | HTR1AHTR2BSIGMAR1 | |
| SCHEMBL7032960 | 0.72 | HTR2B (0.42) | KMT2AMEN1ALDH1A1MAPTGAA | |
| SCHEMBL31432548 | 0.71 | SCN9A (0.40) | KMT2ASMN1; SMN2ALDH1A1MAPTMTNR1A | |
| SCHEMBL7177095 | 0.69 | AKR1B1 (0.55) | ALDH1A1MAPTGAANPC1RAB9A | |
| SCHEMBL28608472 | 0.69 | SMN1; SMN2 (0.50) | KMT2AMEN1SMN1; SMN2ALDH1A1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644364-A1 | TETRAZOL BENZOFURANCARBOXAMIDES WITH PI3K ACTIVITY AS THERAPEUTIC AGENTS | Warner-Lambert Company LLC (US) | 2006-04-12 | — | — | EP | disclosed |
| US-20050020631-A1 | 3-Substituted benzofurans as therapeutic agents | GOGLIOTTI ROCCO DEAN (US) | 2005-01-27 | — | — | US | disclosed |
| WO-2004108709-A1 | TETRAZOL BENZOFURANCARBOXAMIDES WITH P13K AKTIVITY AS THERAPEUTIC AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2004-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020631-A1 | 3-Substituted benzofurans as therapeutic agents | CYP4F11, BPTF, F3 | KMT2A 3196/4885MEN1 1438/4885SMN1; SMN2 2260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.