Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.53 |
| ▸ | NPC1 | O15118 | 8/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984531 | 0.76 | MEN1 (0.53) | MEN1KMT2ANPC1RAB9ATP53 | |
| SCHEMBL5734580 | 0.74 | KMT2A (0.45) | MEN1KMT2ATP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL11598538 | 0.74 | NPC1 (0.67) | MEN1KMT2ANPC1RAB9ATP53 | |
| SCHEMBL18103399 | 0.71 | NPC1 (0.53) | MEN1KMT2ANPC1RAB9ATP53 | |
| SCHEMBL10960859 | 0.70 | KMT2A (1.00) | MEN1KMT2ANPC1RAB9ATP53 | |
| SCHEMBL7189487 | 0.69 | NPC1 (0.72) | MEN1KMT2ANPC1RAB9ATP53 | |
| SCHEMBL7159826 | 0.68 | MEN1 (0.60) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14112088 | 0.68 | MEN1 (0.80) | MEN1KMT2ANPC1RAB9ATP53 | |
| SCHEMBL7120591 | 0.67 | TAS1R3 (0.70) | MEN1KMT2ANPC1TP53SMN1; SMN2 | |
| SCHEMBL10708495 | 0.67 | KDM4E (0.57) | MEN1KMT2ANPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0930883-B1 | NEUROTROPHIN ANTAGONISTS FOR THE TREATMENT OF EPILEPSY, ALZHEIMER'S DISEASE AND PAIN | ALLELIX BIOPHARMA (CA) | 2006-01-11 | — | — | EP | claimed |