SCHEMBL10708495

SCHEMBL10708495

CCOc1ccc(NC(=O)c2ccc3c4ccc(C(=O)O)c5c(C(=O)O)ccc(c6ccc(C(=O)Nc7ccc(OCC)cc7)c2c36)c54)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.57
ALDH1A1 P00352 3/20 0.57
GAA P10253 1/20 0.57
ALOX15 P16050 1/20 0.57
NPC1 O15118 9/20 0.56
RAB9A P51151 8/20 0.56
KMT2A Q03164 7/20 0.56
MEN1 O00255 6/20 0.56
TP53 P04637 4/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
HTT P42858 2/20 0.56
LMNA P02545 2/20 0.56
MAPT P10636 3/20 0.54
MAPK1 P28482 2/20 0.54
ATM Q13315 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
GPR55 Q9Y2T6 1/20 0.54
POLB P06746 2/20 0.53
APOBEC3A P31941 1/20 0.53
APOBEC3G Q9HC16 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9323158 0.85 NPC1 (0.54) ALDH1A1GAAALOX15NPC1RAB9A
SCHEMBL11053315 0.85 MAPT (0.52) KDM4EALDH1A1GAAALOX15NPC1
SCHEMBL18103399 0.84 NPC1 (0.53) KDM4EALDH1A1GAAALOX15NPC1
SCHEMBL7828898 0.81 RAB9A (0.74) KDM4EALDH1A1GAAALOX15NPC1
SCHEMBL823150 0.80 RAB9A (0.50) KDM4EALDH1A1GAANPC1RAB9A
SCHEMBL10708453 0.80 RAB9A (0.50) KDM4EALDH1A1GAANPC1RAB9A
SCHEMBL7773657 0.79 LMNA (0.50) KDM4EALDH1A1GAAKMT2AMEN1
SCHEMBL7781186 0.79 MEN1 (0.50) KDM4EALDH1A1GAANPC1RAB9A
SCHEMBL1096405 0.78 ALDH1A1 (0.62) KDM4EALDH1A1NPC1RAB9AKMT2A
SCHEMBL823148 0.78 ALDH1A1 (0.62) KDM4EALDH1A1NPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0114482-B1 A PHOTOSENSITIVE COMPOSITION FOR ELECTROPHOTOGRAPHY MITA INDUSTRIAL CO. LTD. (JP) 1988-09-14 EP claimed
EP-3907554-B1 OPTICAL SHEET AND OPTICAL COMPONENT SUMITOMO BAKELITE CO (JP) 2023-05-03 EP disclosed
US-20220043283-A1 OPTICAL SHEET AND OPTICAL COMPONENT SUMITOMO BAKELITE CO., LTD. (JP) 2022-02-10 US disclosed
EP-3690504-B1 OPTICAL SHEET AND OPTICAL COMPONENT SUMITOMO BAKELITE CO (JP) 2022-01-12 EP disclosed
EP-3916437-A1 OPTICAL SHEET AND OPTICAL COMPONENT Sumitomo Bakelite Co.Ltd. (JP) 2021-12-01 EP disclosed
EP-3907554-A1 OPTICAL SHEET AND OPTICAL COMPONENT Sumitomo Bakelite Co.Ltd. (JP) 2021-11-10 EP disclosed
US-11119260-B2 Optical sheet and optical component SUMITOMO BAKELITE CO., LTD. (JP) 2021-09-14 US disclosed
US-20200249378-A1 OPTICAL SHEET AND OPTICAL COMPONENT SUMITOMO BAKELITE CO., LTD. (JP) 2020-08-06 US disclosed
EP-3690504-A1 OPTICAL SHEET AND OPTICAL COMPONENT Sumitomo Bakelite Co., Ltd. (JP) 2020-08-05 EP disclosed
EP-0114482-B1 A PHOTOSENSITIVE COMPOSITION FOR ELECTROPHOTOGRAPHY MITA INDUSTRIAL CO. LTD. (JP) 1988-09-14 EP disclosed
EP-0100581-B1 PHOTOSENSITIVE MATERIAL FOR ELECTROPHOTOGRAPHY MITA INDUSTRIAL CO. LTD. (JP) 1987-08-26 EP disclosed
EP-0062540-B1 PHOTOSENSITIVE COMPOSITION FOR ELECTROPHOTOGRAPHY MITA INDUSTRIAL CO. LTD. (JP) 1987-01-14 EP disclosed
EP-0088607-B1 ORGANIC PHOTOSENSITIVE MATERIAL FOR ELECTROPHOTOGRAPHY MITA INDUSTRIAL CO. LTD. (JP) 1986-07-16 EP disclosed
US-4469769-A Photosensitive material for electrophotography contains halo-benzoquinone sensitizer MITA INDUSTRIAL CO. LTD. (JP) 1984-09-04 US disclosed
US-4447514-A PYRYLENE PIGMENT MITA INDUSTRIAL CO., LTD. (JP) 1984-05-08 US disclosed
US-4438187-A POLYVINYLCARBAZOLE, AND PERYLENE PIGMENT MITA INDUSTRIAL CO. LTD. (JP) 1984-03-20 US disclosed
EP-0100581-A2 Photosensitive material for electrophotography MITA INDUSTRIAL CO. LTD. (JP) 1984-02-15 EP disclosed
EP-0088607-A2 Organic photosensitive material for electrophotography MITA INDUSTRIAL CO. LTD. (JP) 1983-09-14 EP disclosed