Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | OXTR | P30559 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | CDC7 | O00311 | 3/20 | 0.40 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5733833 | 0.93 | CNR1 (0.44) | CNR1MAPTOXTRALDH1A1RAB9A | |
| SCHEMBL5734359 | 0.84 | F10 (0.54) | MAPTSMN1; SMN2GAAF10F2 | |
| SCHEMBL5735603 | 0.83 | OXTR (0.43) | CNR1MAPTOXTRALDH1A1RAB9A | |
| SCHEMBL5735531 | 0.83 | MAPT (0.53) | CNR1MAPTOXTRALDH1A1RAB9A | |
| SCHEMBL5737420 | 0.83 | F10 (0.56) | CNR1MAPTOXTRALDH1A1CDC7 | |
| SCHEMBL6306860 | 0.82 | LSS (0.50) | HRH4ALDH1A1RAB9ANPC1L3MBTL1 | |
| SCHEMBL5733266 | 0.81 | MAPT (0.43) | CNR1MAPTOXTRALDH1A1RAB9A | |
| SCHEMBL5735064 | 0.81 | LSS (0.54) | CNR1MAPTOXTRALDH1A1RAB9A | |
| SCHEMBL5735605 | 0.80 | OXTR (0.42) | CNR1MAPTOXTRALDH1A1RAB9A | |
| SCHEMBL5734565 | 0.80 | ALDH1A1 (0.45) | CNR1MAPTOXTRALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986551-B1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL (JP) | 2006-08-02 | — | — | EP | disclosed |
| US-6359134-B1 | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-03-19 | — | — | US | disclosed |