SCHEMBL573604

SCHEMBL573604

Nc1ccc2c(-c3ccccc3)cccc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 1/20 0.53
ALDH1A1 P00352 7/20 0.48
HSD17B10 Q99714 5/20 0.48
CYP3A4 P08684 3/20 0.48
PRKCZ Q05513 1/20 0.47
KMT2A Q03164 5/20 0.47
MEN1 O00255 4/20 0.47
MAPT P10636 4/20 0.47
HPGD P15428 4/20 0.47
KDM4E B2RXH2 3/20 0.47
MPI P34949 1/20 0.47
TDP1 Q9NUW8 2/20 0.47
MAOA P21397 1/20 0.47
ALOX15 P16050 1/20 0.47
CASP1 P29466 1/20 0.47
CASP7 P55210 1/20 0.47
HBB P68871 1/20 0.47
HIF1A Q16665 1/20 0.47
CDK4 P11802 1/20 0.47
CCND1 P24385 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11378957 0.85 CDK4 (0.57) PLAUALDH1A1HSD17B10CYP3A4PRKCZ
SCHEMBL24079294 0.82 CA12 (0.50) ALDH1A1HSD17B10CYP3A4PRKCZKMT2A
SCHEMBL19579514 0.82 CA12 (0.50) ALDH1A1HSD17B10CYP3A4PRKCZKMT2A
SCHEMBL29830445 0.81 CA12 (0.52) ALDH1A1HSD17B10CYP3A4PRKCZKMT2A
SCHEMBL26021771 0.80 CDK4 (0.50) ALDH1A1HSD17B10CYP3A4PRKCZKMT2A
SCHEMBL31670654 0.80 ALDH1A1 (0.60) ALDH1A1HSD17B10CYP3A4PRKCZKMT2A
SCHEMBL10043791 0.80 ALDH1A1 (0.60) ALDH1A1HSD17B10CYP3A4PRKCZKMT2A
SCHEMBL598398 0.80 HSD17B1 (0.59) ALDH1A1CYP3A4KMT2AMEN1MAPT
SCHEMBL22325646 0.80 CA12 (0.48) ALDH1A1HSD17B10CYP3A4PRKCZKMT2A
SCHEMBL29473516 0.80 CA12 (0.48) ALDH1A1HSD17B10CYP3A4PRKCZKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3862360-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2024-07-03 EP disclosed
EP-4306612-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2024-01-17 EP disclosed
EP-4274402-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME Samsung Display Co., Ltd. (KR) 2023-11-08 EP disclosed
EP-4274405-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2023-11-08 EP disclosed
EP-3722301-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2023-11-01 EP disclosed
EP-3725793-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2023-10-11 EP disclosed
EP-3851443-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2023-09-13 EP disclosed
EP-4101908-A1 COMPOSITION, LAYER INCLUDING THE COMPOSITION, LIGHT-EMITTING DEVICE INCLUDING THE COMPOSITION, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2022-12-14 EP disclosed
WO-2022129114-A1 NITROGENOUS COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-06-23 WO disclosed
WO-2022129113-A1 NITROGENOUS HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-06-23 WO disclosed
US-20150299189-A1 NOVEL AMINE DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2015-10-22 US disclosed
US-20150299189-A1 NOVEL AMINE DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2015-10-22 US disclosed
US-20150299189-A1 NOVEL AMINE DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2015-10-22 US disclosed
EP-2915804-A1 NOVEL AMINE DERIVATIVE OR SALT THEREOF Toyama Chemical Co., Ltd. (JP) 2015-09-09 EP disclosed
EP-2809734-A1 INKJET INK AND INKJET RECORDING DEVICE Ricoh Company, Ltd. (JP) 2014-12-10 EP disclosed
WO-2014069510-A1 NOVEL AMINE DERIVATIVE OR SALT THEREOF 富山化学工業株式会社 (JP) 2014-05-08 WO disclosed
WO-2013115344-A1 INKJET INK AND INKJET RECORDING DEVICE RICOH COMPANY, LTD. (JP) 2013-08-08 WO disclosed
EP-2601271-A1 INKJET INK, INK CARTRIDGE, INKJET RECORDING METHOD, INKJET RECORDING DEVICE, AND INKJET RECORDED MATTER Ricoh Company, Limited (JP) 2013-06-12 EP disclosed
WO-2012018098-A1 INKJET INK, INK CARTRIDGE, INKJET RECORDING METHOD, INKJET RECORDING DEVICE, AND INKJET RECORDED MATTER RICOH COMPANY, LTD. (JP) 2012-02-09 WO disclosed
US-3993847-A RUBBER BONDED TO FERROUS METAL, INTERPOLYMER OF CONJUGATED DIENE AND HETEROCYCLIC NITROGEN BASE HONNY CHEMICALS COMPANY, LTD. (JA) 1976-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150299189-A1 NOVEL AMINE DERIVATIVE OR SALT THEREOF HRH4, CLIC4, KRT18 PLAU 4542/4885ALDH1A1 1842/4885HSD17B10 1098/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.