Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Irampanel SCHEMBL678128 | 0.90 | HTR7 (0.63) | NPSR1TTRHTR7MAPTHSD17B10 | |
| SCHEMBL7955292 | 0.89 | TTR (0.55) | NPSR1TTRHTR7MAPTHSD17B10 | |
| SCHEMBL7958390 | 0.89 | TTR (0.55) | NPSR1TTRHTR7MAPTHSD17B10 | |
| Irampanel SCHEMBL6879876 | 0.89 | HTR7 (0.62) | NPSR1TTRHTR7MAPTHSD17B10 | |
| SCHEMBL7955222 | 0.88 | TTR (0.54) | NPSR1TTRHTR7MAPTHSD17B10 | |
| SCHEMBL7956790 | 0.88 | TTR (0.54) | NPSR1TTRHTR7MAPTHSD17B10 | |
| SCHEMBL7961594 | 0.87 | MAPT (0.59) | NPSR1TTRHTR7MAPTHSD17B10 | |
| SCHEMBL7956669 | 0.87 | TTR (0.56) | NPSR1TTRHTR7MAPTHSD17B10 | |
| SCHEMBL5959899 | 0.87 | TTR (0.72) | NPSR1TTRHTR7MAPTHSD17B10 | |
| SCHEMBL7956917 | 0.87 | HTR7 (0.44) | NPSR1TTRHTR7MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934288-B1 | OXADIAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2006-01-04 | — | — | EP | disclosed |
| US-6277872-B1 | ANTIISCHEMIC AGENTS; BRAIN DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 2001-08-21 | — | — | US | disclosed |