Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947658 | 0.91 | SMN1; SMN2 (0.56) | NPSR1HTR7NPC1MEN1KMT2A | |
| Irampanel SCHEMBL678128 | 0.90 | HTR7 (0.63) | TTRNPSR1HTR7NPC1MEN1 | |
| SCHEMBL7955292 | 0.89 | TTR (0.55) | TTRNPSR1HTR7NPC1MEN1 | |
| SCHEMBL7958390 | 0.89 | TTR (0.55) | TTRNPSR1HTR7NPC1MEN1 | |
| Irampanel SCHEMBL6879876 | 0.89 | HTR7 (0.62) | TTRNPSR1HTR7NPC1MEN1 | |
| SCHEMBL7956772 | 0.89 | TTR (0.52) | TTRNPSR1HTR7NPC1MEN1 | |
| SCHEMBL7955222 | 0.88 | TTR (0.54) | TTRNPSR1HTR7NPC1MEN1 | |
| SCHEMBL5736080 | 0.88 | NPSR1 (0.54) | TTRNPSR1HTR7NPC1MEN1 | |
| SCHEMBL7958824 | 0.88 | SMN1; SMN2 (0.51) | TTRNPSR1HTR7NPC1MEN1 | |
| SCHEMBL7961527 | 0.88 | SMN1; SMN2 (0.55) | TTRNPSR1HTR7NPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277872-B1 | ANTIISCHEMIC AGENTS; BRAIN DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 2001-08-21 | — | — | US | disclosed |