Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.60 |
| ▸ | PKM | P14618 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | GAA | P10253 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6201253 | 0.88 | F10 (0.61) | F10PKMLMNAGAASMN1; SMN2 | |
| SCHEMBL5736557 | 0.88 | GAA (0.63) | F10PKMLMNAGAASMN1; SMN2 | |
| SCHEMBL5735336 | 0.85 | GRM5 (0.64) | F10PKMLMNAATMGRM5 | |
| SCHEMBL7074610 | 0.84 | GAA (0.59) | F10PKMLMNAGAASMN1; SMN2 | |
| SCHEMBL7073572 | 0.81 | PKM (0.55) | F10PKMLMNAGAASMN1; SMN2 | |
| SCHEMBL9951915 | 0.80 | PKM (0.80) | PKMLMNAGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL7074612 | 0.80 | PLG (0.56) | F10PKMLMNAGAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5733597 | 0.79 | PKM (0.56) | F10PKMLMNAGAASMN1; SMN2 | |
| SCHEMBL6180621 | 0.79 | F10 (0.76) | F10LMNAATMF2L3MBTL1 | |
| SCHEMBL5193868 | 0.78 | ATM (0.71) | F10LMNAGAASMN1; SMN2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986551-B1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL (JP) | 2006-08-02 | — | — | EP | disclosed |
| US-6359134-B1 | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-0986551-A1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Pharmaceutical Company Limited (JP) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998054164-A1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-03 | — | — | WO | disclosed |