Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | XDH | P47989 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | FOS | P01100 | 1/20 | 0.41 |
| ▸ | JUN | P05412 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL403150 | 0.87 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL3228101 | 0.85 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL3229462 | 0.83 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL4384415 | 0.83 | SMN1; SMN2 (0.63) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL11782992 | 0.82 | MEN1 (0.50) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL28758109 | 0.82 | KDM4E (0.59) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL6760385 | 0.81 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL27576873 | 0.81 | MEN1 (0.53) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL22283553 | 0.80 | NPC1 (0.60) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL6737103 | 0.80 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986551-B1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL (JP) | 2006-08-02 | — | — | EP | disclosed |
| US-6359134-B1 | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-0986551-A1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Pharmaceutical Company Limited (JP) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998054164-A1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-03 | — | — | WO | disclosed |