Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5735479 | 0.81 | ALDH1A1 (0.51) | ALDH1A1HTTLMNAKDM4EMAPT | |
| SCHEMBL1085471 | 0.76 | LMNA (0.57) | ALDH1A1HTTLMNAKDM4EMAPT | |
| SCHEMBL14266795 | 0.74 | LMNA (0.54) | ALDH1A1HTTLMNAKDM4EMAPT | |
| SCHEMBL1085423 | 0.73 | ATM (0.68) | ALDH1A1HTTLMNAKDM4EMAPT | |
| SCHEMBL6307904 | 0.72 | MAPT (0.66) | ALDH1A1HTTLMNAKDM4EMAPT | |
| SCHEMBL2025929 | 0.72 | CNR1 (0.47) | ALDH1A1HTTLMNAKDM4EMAPT | |
| SCHEMBL3539039 | 0.71 | ATM (0.59) | ALDH1A1HTTLMNAKDM4EMAPT | |
| SCHEMBL398942 | 0.71 | S1PR1 (0.53) | ALDH1A1HTTLMNAKDM4EMAPT | |
| SCHEMBL5736158 | 0.71 | NOTUM (0.41) | ALDH1A1HTTKDM4EMAPTPOLB | |
| SCHEMBL1085475 | 0.70 | ALDH1A1 (0.51) | ALDH1A1HTTLMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105375-B1 | TRIFLUOROMETHYLPYRROLCARBOXAMIDES USEFUL AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-02-22 | — | — | EP | disclosed |
| US-6365620-B2 | Trifluoromethylpyrrolcarboxamides | SYNGENTA CROP PROTECTION, INC. | 2002-04-02 | — | — | US | disclosed |
| US-20020019541-A1 | Trifluoromethylpyrrolcarboxamides | EBERLE MARTIN (CH) | 2002-02-14 | — | — | US | disclosed |
| EP-1105375-A1 | TRIFLUORO METHYLPYRROL CARBOXAMIDES | Syngenta Participations AG (CH) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000009482-A1 | TRIFLUORO METHYLPYRROL CARBOXAMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019541-A1 | Trifluoromethylpyrrolcarboxamides | CBR3, CBR1, DDT | ALDH1A1 993/4885HTT 1826/4885LMNA 2380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.