Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | HPGD | P15428 | 3/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NQO1 | P15559 | 1/20 | 0.49 |
| ▸ | CELA1 | Q9UNI1 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MGAM | O43451 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782390 | 0.88 | KDM4E (0.59) | KDM4EALDH1A1HPGDSMN1; SMN2MAPK1 | |
| SCHEMBL758464 | 0.84 | KDM4E (0.67) | KDM4EALDH1A1HPGDSMN1; SMN2MAPK1 | |
| SCHEMBL4573629 | 0.84 | KDM4E (1.00) | KDM4EALDH1A1HPGDSMN1; SMN2MAPK1 | |
| SCHEMBL25963177 | 0.83 | KDM4E (0.50) | KDM4EALDH1A1HPGDSMN1; SMN2MAPK1 | |
| SCHEMBL25338376 | 0.82 | KDM4E (0.49) | KDM4EALDH1A1HPGDSMN1; SMN2MAPK1 | |
| SCHEMBL5734812 | 0.82 | KDM4E (0.72) | KDM4EALDH1A1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL5737276 | 0.81 | MCL1 (0.69) | KDM4EALDH1A1HPGDSMN1; SMN2MAPK1 | |
| SCHEMBL4924288 | 0.80 | KDM4E (1.00) | KDM4EALDH1A1HPGDSMN1; SMN2MAPK1 | |
| SCHEMBL11126153 | 0.80 | KDM4E (0.71) | KDM4EALDH1A1HPGDSMN1; SMN2MAPK1 | |
| SCHEMBL17179764 | 0.78 | CFTR (0.47) | KDM4EALDH1A1HPGDSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250171460-A1 | INDUCERS OF KLF2 AND METHODS OF USE THEREOF | RIPARIAN PHARMACEUTICALS, INC. (US) | 2025-05-29 | — | — | US | disclosed |
| EP-4476229-A1 | INDUCERS OF KLF2 AND METHODS OF USE THEREOF | Riparian Pharmaceuticals, Inc. (US) | 2024-12-18 | — | — | EP | disclosed |
| CN-118974057-A | KLF2 inducers and methods of use thereof | 里帕里安制药股份有限公司 | 2024-11-15 | — | — | CN | disclosed |
| WO-2023150374-A1 | INDUCERS OF KLF2 AND METHODS OF USE THEREOF | RIPARIAN PHARMACEUTICALS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |
| WO-2023150374-A1 | INDUCERS OF KLF2 AND METHODS OF USE THEREOF | RIPARIAN PHARMACEUTICALS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |
| EP-1644364-A1 | TETRAZOL BENZOFURANCARBOXAMIDES WITH PI3K ACTIVITY AS THERAPEUTIC AGENTS | Warner-Lambert Company LLC (US) | 2006-04-12 | — | — | EP | disclosed |
| US-20050020631-A1 | 3-Substituted benzofurans as therapeutic agents | GOGLIOTTI ROCCO DEAN (US) | 2005-01-27 | — | — | US | disclosed |
| WO-2004108709-A1 | TETRAZOL BENZOFURANCARBOXAMIDES WITH P13K AKTIVITY AS THERAPEUTIC AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2004-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250171460-A1 | INDUCERS OF KLF2 AND METHODS OF USE THEREOF | SREBF2, LIPG, KLF5 | KDM4E 999/4885ALDH1A1 1828/4885HPGD 662/4885 |
| US-20050020631-A1 | 3-Substituted benzofurans as therapeutic agents | CYP4F11, BPTF, F3 | KDM4E 2213/4885ALDH1A1 103/4885HPGD 1979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.