KLF5 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL683715	0.76	3/20
SCHEMBL95542	0.69	3/20
SCHEMBL95543	0.69	3/20
SCHEMBL95161	0.64	3/20
SCHEMBL684542	0.63	3/20
SCHEMBL469274	0.62	3/20
SCHEMBL684841	0.61	3/20
SCHEMBL565231	0.40	3/20
SCHEMBL565921	0.40	3/20
Ouabain (SCHEMBL15433)	1.00	2/20
Ouabain (SCHEMBL230974)	1.00	2/20
Dihydroouabain (SCHEMBL412984)	1.00	2/20
Ouabain (SCHEMBL413472)	0.99	2/20
SCHEMBL684944	0.72	2/20
SCHEMBL684539	0.71	2/20
SCHEMBL685183	0.69	2/20
SCHEMBL683765	0.68	2/20
SCHEMBL107323	0.67	2/20
SCHEMBL684842	0.66	2/20
SCHEMBL204726	0.66	2/20

Clinical trials — most relevant to KLF5 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Efficacy and Safety of Pioglitazone in Treating Subjects With Vascular Complications Associated With Type 2 Diabetes Mellitus.	PHASE4	COMPLETED
Deciphering Effects of Thalidomide on Red Blood Cells in Transfusion Dependents Beta Thalassemia Patients	PHASE3	COMPLETED
Paclitaxel Eluting Covered Metallic Stent for Unresectable Malignant Bile Duct Obstruction	PHASE3	COMPLETED
The Use of Inhaled Corticosteroids in the Treatment of Asthma is Children in the Emergency Room	PHASE2/PHASE3	COMPLETED
Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers	PHASE2	NOT_YET_RECRUITING
Safety and Dose Escalation Study of Zinc Supplementation in Critically Ill Children	PHASE1/PHASE2	COMPLETED
68 Ga-NODAGA-E[c(RGDγK)]2: Positron Emission Tomography Tracer for Imaging of Myocardial Angiogenesis	PHASE2	COMPLETED
Treatment Duration Increment and Pharmacodynamic Study of CX-4945 in Patients With Basal Cell Carcinoma (BCC)	PHASE1	COMPLETED
Can Gluten-free Diet Prevent the Destruction of Beta-cells During Remission?	EARLY_PHASE1	UNKNOWN
Osteoclast Inhibition and Bone Formation	EARLY_PHASE1	COMPLETED
EKLF Gene Expression in β-thalassemia	nan	NOT_YET_RECRUITING
Tissue Expression of Krüppel-Like Factors 4 and 7 in Bone Tumors	nan	RECRUITING
Detection of Krupple Like Factor -1(KLF1/ EKLF) DNA Mutations in Beta Thalassemia Patients	nan	NOT_YET_RECRUITING
Clinical Study of Desuzumab in the Treatment of Knee Osteoarthritis	nan	RECRUITING
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Mild Intermittent Hypoxia and Its Multipronged Effect on Sleep Apnea	nan	RECRUITING
Klotho _ LRP-6 _ Gastric Adenocarcinoma	nan	UNKNOWN
Observational Study to Assess Glycosylated Hemoglobin Changes After 6 Months of Treatment With Pioglitazone.	nan	COMPLETED
Transcription Factor Runx2 in Necrotic Femoral Head Tissue	nan	COMPLETED
Identification of Viable Human Embryos Using Three Different Methods	nan	COMPLETED
EPIgenetics and in Vivo Resistance of Chronic Myeloid Leukemia Stem Cells to Tyrosine Kinase Inhibitors	nan	UNKNOWN
TIGIT in Patients With Chronic Myeloid Leukemia	nan	UNKNOWN
Cell Signaling and Resistance to Oxidative Stress: Effects of Aging and Exercise	nan	COMPLETED
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders	nan	COMPLETED
Gene Expression Variation and Implant Wound Healing Among Smokers and Diabetics	nan	COMPLETED
Effect of Post Covid-19 Hypoxia on Placenta of Normal Pregnant Women: A Possible Role of Hypoxia Inducible Factor-1α.	nan	UNKNOWN
A Study to See if Low Level Laser Light Therapy (LLLT) Can Improve the Condition of Nonalcoholic Steatohepatitis (NASH)	nan	WITHDRAWN
Azoospermia Patients	nan	RECRUITING
Comparison Of Efficacy Of Tazarotene 0.045% Vs Halobetasol Propionate 0.01% Lotion For Treatment of Scalp Psoriasis	nan	COMPLETED
Genetic Analysis of Keloids	nan	RECRUITING

Related proteins — ESM-2 sequence neighbours (a KLF5 binder may also engage these)

Protein	Name	Similarity
Q9Z0Z7	—	1.000	Q9Z0Z7 →
Q91904	—	0.995	Q91904 →
P57682	—	0.993	P57682 →
O94900	—	0.993	O94900 →
Q8AWG6	—	0.992	Q8AWG6 →
O89038	—	0.992	O89038 →
P43300	—	0.992	P43300 →
P53035	—	0.992	P53035 →
Q91661	—	0.992	Q91661 →
G4NBR8	—	0.992	G4NBR8 →
Q91660	—	0.992	Q91660 →
Q66JW3	—	0.992	Q66JW3 →
P61753	—	0.992	P61753 →
P08152	—	0.992	P08152 →
P48436	—	0.992	P48436 →
Q91905	—	0.992	Q91905 →
Q6NSM8	—	0.992	Q6NSM8 →
P0DH89	—	0.992	P0DH89 →
P46200	—	0.992	P46200 →
Q8BUR3	—	0.991	Q8BUR3 →
Q9BG89	—	0.991	Q9BG89 →
P57074	—	0.991	P57074 →
G1X9A9	—	0.991	G1X9A9 →
P51774	—	0.991	P51774 →
A4II20	—	0.991	A4II20 →
Q99958	—	0.991	Q99958 →
Q9PVY9	—	0.991	Q9PVY9 →
O93529	—	0.991	O93529 →
Q28EM1	—	0.991	Q28EM1 →
Q9DE25	—	0.991	Q9DE25 →