Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL983021 | 0.83 | RAB9A (0.69) | NPC1RAB9AL3MBTL1HTR2CSMN1; SMN2 | |
| SCHEMBL13506550 | 0.81 | NPC1 (0.54) | NPC1RAB9AL3MBTL1SMN1; SMN2GAA | |
| SCHEMBL14745997 | 0.79 | NPC1 (0.53) | NPC1RAB9AL3MBTL1SMN1; SMN2GAA | |
| SCHEMBL17675590 | 0.77 | RAB9A (0.64) | NPC1RAB9AL3MBTL1HTR2CSMN1; SMN2 | |
| SCHEMBL3167334 | 0.77 | RAB9A (0.57) | NPC1RAB9AL3MBTL1SMN1; SMN2GAA | |
| SCHEMBL3182929 | 0.76 | NPC1 (0.56) | NPC1RAB9AL3MBTL1HTR2CSMN1; SMN2 | |
| SCHEMBL22638725 | 0.75 | NPC1 (0.63) | NPC1RAB9AL3MBTL1HTR2CSLC6A3 | |
| SCHEMBL2539997 | 0.75 | NPC1 (0.67) | NPC1RAB9AL3MBTL1HTR2CSLC6A3 | |
| SCHEMBL2876191 | 0.74 | NPC1 (0.53) | NPC1RAB9AL3MBTL1SMN1; SMN2GAA | |
| SCHEMBL7469639 | 0.72 | NPC1 (1.00) | NPC1RAB9AL3MBTL1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549309-A4 | SOMATOSTATIN ANALOGUE COMPOUNDS | CHEMBRIDGE RES LAB INC (US) | 2006-05-17 | — | — | EP | disclosed |
| EP-1549309-A2 | SOMATOSTATIN ANALOGUE COMPOUNDS | ChemBridge Research Laboratories, Inc. (US) | 2005-07-06 | — | — | EP | disclosed |
| US-6872827-B2 | Somatostatin analogue compounds | CHEMBRIDGE RESEARCH LABORATORIES, INC. (US) | 2005-03-29 | — | — | US | disclosed |
| US-20040019069-A1 | Somatostatin analogue compounds | CHEMBRIDGE CORPORATION | 2004-01-29 | — | — | US | disclosed |
| WO-2003090677-A2 | SOMATOSTATIN ANALOGUE COMPOUNDS | CHEMBRIDGE RESEARCH LAB., LLC (US) | 2003-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019069-A1 | Somatostatin analogue compounds | SSTR2, SSTR1, SSTR4 | NPC1 2071/4885RAB9A 1902/4885L3MBTL1 3630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.