Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | REN | P00797 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983340 | 0.99 | HDAC1 (0.53) | HDAC1HDAC3HDAC2NCOR2L3MBTL1 | |
| SCHEMBL7973240 | 0.99 | HDAC1 (0.53) | HDAC1HDAC3HDAC2NCOR2L3MBTL1 | |
| SCHEMBL1848202 | 0.96 | HDAC1 (0.52) | HDAC1HDAC3HDAC2NCOR2L3MBTL1 | |
| SCHEMBL7982368 | 0.92 | REN (0.53) | HDAC1HDAC3HDAC2NCOR2L3MBTL1 | |
| SCHEMBL7972070 | 0.92 | REN (0.53) | HDAC1HDAC3HDAC2NCOR2L3MBTL1 | |
| SCHEMBL7982499 | 0.92 | REN (0.53) | HDAC1HDAC3HDAC2NCOR2L3MBTL1 | |
| SCHEMBL7983610 | 0.92 | REN (0.53) | HDAC1HDAC3HDAC2NCOR2L3MBTL1 | |
| SCHEMBL7986481 | 0.92 | REN (0.53) | HDAC1HDAC3HDAC2NCOR2L3MBTL1 | |
| SCHEMBL8525848 | 0.92 | HDAC3 (0.56) | HDAC1HDAC3HDAC2NCOR2L3MBTL1 | |
| SCHEMBL8021840 | 0.90 | HDAC3 (0.55) | HDAC1HDAC3HDAC2NCOR2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260001846-A1 | SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | SERVIER LAB (FR) | 2026-01-01 | — | — | US | disclosed |
| EP-4551566-A1 | NEW SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | Les Laboratoires Servier (FR) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024008941-A1 | NEW SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2024-01-11 | — | — | WO | disclosed |
| EP-1549309-A4 | SOMATOSTATIN ANALOGUE COMPOUNDS | CHEMBRIDGE RES LAB INC (US) | 2006-05-17 | — | — | EP | disclosed |
| EP-1549309-A2 | SOMATOSTATIN ANALOGUE COMPOUNDS | ChemBridge Research Laboratories, Inc. (US) | 2005-07-06 | — | — | EP | disclosed |
| US-6872827-B2 | Somatostatin analogue compounds | CHEMBRIDGE RESEARCH LABORATORIES, INC. (US) | 2005-03-29 | — | — | US | disclosed |
| US-20040019069-A1 | Somatostatin analogue compounds | CHEMBRIDGE CORPORATION | 2004-01-29 | — | — | US | disclosed |
| WO-2003090677-A2 | SOMATOSTATIN ANALOGUE COMPOUNDS | CHEMBRIDGE RESEARCH LAB., LLC (US) | 2003-11-06 | — | — | WO | disclosed |
| US-6214833-B1 | MADE BY ACYLATION | ZAMBON GROUP S.P.A. (IT) | 2001-04-10 | — | — | US | disclosed |
| US-6114394-A | Polyamine derivatives as radioprotective agents | MERRELL PHARMACEUTICALS INC. (US) | 2000-09-05 | — | — | US | disclosed |
| EP-0686142-B1 | POLYAMINE DERIVATIVES AS RADIOPROTECTIVE AGENTS | MERRELL PHARMA INC (US) | 1998-12-30 | — | — | EP | disclosed |
| WO-1998043972-A1 | PYRIMIDINONE-1,3-OXATHIOLANE DERIVATIVES WITH ANTIVIRAL ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 1998-10-08 | — | — | WO | disclosed |
| EP-0399519-B1 | Potentiating cell-mediated immunity utilizing polyamine derivatives | MERRELL PHARMA INC (US) | 1996-08-07 | — | — | EP | disclosed |
| EP-0686142-A1 | POLYAMINE DERIVATIVES AS RADIOPROTECTIVE AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1995-12-13 | — | — | EP | disclosed |
| EP-0662829-A1 | POLYAMINE DERIVATIVES AS ANTI-CYTOMEGALOVIRAL AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1995-07-19 | — | — | EP | disclosed |
| WO-1994019311-A1 | POLYAMINE DERIVATIVES AS RADIOPROTECTIVE AGENTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-09-01 | — | — | WO | disclosed |
| WO-1994007480-A1 | POLYAMINE DERIVATIVES AS ANTI-CYTOMEGALOVIRAL AGENTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-04-14 | — | — | WO | disclosed |
| EP-0277635-B1 | Novel polyamine derivatives | MERRELL DOW PHARMA (US) | 1994-01-05 | — | — | EP | disclosed |
| EP-0399519-A2 | Potentiating cell-mediated immunity utilizing polyamine derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1990-11-28 | — | — | EP | disclosed |
| EP-0277635-A2 | Novel polyamine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-08-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260001846-A1 | SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | BCL2, BCL2A1, BAX | HDAC1 102/4885HDAC3 142/4885HDAC2 409/4885 |
| US-20040019069-A1 | Somatostatin analogue compounds | SSTR2, SSTR1, SSTR4 | HDAC1 1411/4885HDAC3 345/4885HDAC2 1125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.