Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.55 |
| ▸ | ESR1 | P03372 | 5/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.55 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3656769 | 0.87 | TSHR (0.51) | TSHRESR1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL21382113 | 0.86 | ALDH1A1 (0.47) | TSHRESR1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL6082056 | 0.86 | TSHR (0.56) | TSHRESR1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL21382246 | 0.85 | MAPK1 (0.46) | TSHRESR1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL6266590 | 0.84 | SMN1; SMN2 (0.49) | TSHRESR1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL4448680 | 0.84 | APP (0.49) | TSHRESR1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL10710710 | 0.83 | TSHR (0.57) | TSHRESR1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8551970 | 0.83 | LTB4R2 (0.55) | TSHRESR1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL12407195 | 0.78 | TSHR (0.48) | TSHRMAPK1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL21382236 | 0.77 | MAPT (0.60) | TSHRSMN1; SMN2LMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311625-B1 | FUNCTIONALIZED PERYLENE TETRACARBOXYLIC ACID DIIMIDES | MAX PLANCK GESELLSCHAFT (DE) | 2006-02-01 | — | — | EP | disclosed |
| US-6916928-B2 | Functionalized perylene tetracarboxylic acid diimides | MAX-PLANCK-GESELLSCHAFT DER WISSENSCHAFTENE.V. (DE) | 2005-07-12 | — | — | US | disclosed |
| US-20040024151-A1 | Functionalized perylene tetracarboxylic acid diimides | MAX-PLANCK-GESELLSCHAFT DER WISSENSCHAFTENE. V. (DE) | 2004-02-05 | — | — | US | disclosed |