Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.44 |
| ▸ | RNF4 | P78317 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5737663 | 0.83 | TSHR (0.55) | LTB4R2TSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL3656769 | 0.82 | TSHR (0.51) | LTB4R2TSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL9370539 | 0.79 | TSHR (0.54) | TSHRMAPK1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL11430998 | 0.77 | TSHR (0.50) | TSHRMAPK1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL11546490 | 0.77 | TSHR (0.50) | LTB4R2TSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL6266590 | 0.77 | SMN1; SMN2 (0.49) | LTB4R2TSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL1925076 | 0.77 | ALDH1A1 (0.59) | L3MBTL1ALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL7473118 | 0.77 | LTB4R2 (0.49) | LTB4R2ALDH1A1SMN1; SMN2PDK1PDK2 | |
| SCHEMBL1259310 | 0.76 | PDK1 (0.58) | LTB4R2TSHRALDH1A1SMN1; SMN2ESR1 | |
| SCHEMBL4921591 | 0.76 | TSHR (0.49) | LTB4R2TSHRMAPK1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |