SCHEMBL5737745

SCHEMBL5737745

O=C(NCC1CN(c2ccc(C3CCC(O)C(O)C3)cc2)C(=O)O1)C(Cl)Cl

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
F10 P00742 19/20 0.53
F2 P00734 3/20 0.45
ABCB11 O95342 1/20 0.45
ST14 Q9Y5Y6 1/20 0.45
ITGB3 P05106 1/20 0.43
ITGA2B P08514 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5739169 0.90 F10 (0.51) F10F2ITGB3ITGA2B
SCHEMBL5737375 0.88 F10 (0.52) F10ABCB11
SCHEMBL5737890 0.85 F10 (0.48) F10
SCHEMBL5739322 0.83 F10 (0.49) F10F2ITGB3ITGA2B
SCHEMBL5737363 0.83 F10 (0.48) F10F2
SCHEMBL5763117 0.82 F10 (0.54) F10F2ABCB11ST14
SCHEMBL9815512 0.81 F10 (0.64) F10F2
SCHEMBL6619705 0.78 F10 (0.47) F10F2ABCB11ST14
SCHEMBL9815515 0.77 F10 (0.51) F10F2ABCB11ST14
SCHEMBL5221102 0.77 F10 (0.46) F10F2ABCB11ST14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1660488-A1 NOVEL ANTIMICROBIAL ARYLOXAZOLIDINONE COMPOUNDS Warner-Lambert Company LLC (US) 2006-05-31 EP claimed
US-20050065187-A1 Novel antimicrobial aryloxazolidinone compounds GORDEEV MIKHAIL FEDOROVICH (US) 2005-03-24 US claimed
WO-2005019214-A1 NOVEL ANTIMICROBIAL ARYLOXAZOLIDINONE COMPOUNDS WARNER-LAMBERT COMPANY LLC (US) 2005-03-03 WO claimed
EP-1660488-A1 NOVEL ANTIMICROBIAL ARYLOXAZOLIDINONE COMPOUNDS Warner-Lambert Company LLC (US) 2006-05-31 EP disclosed
US-20050065187-A1 Novel antimicrobial aryloxazolidinone compounds GORDEEV MIKHAIL FEDOROVICH (US) 2005-03-24 US disclosed
WO-2005019214-A1 NOVEL ANTIMICROBIAL ARYLOXAZOLIDINONE COMPOUNDS WARNER-LAMBERT COMPANY LLC (US) 2005-03-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050065187-A1 Novel antimicrobial aryloxazolidinone compounds XDH, NQO1, MPO F10 4687/4885F2 3341/4885ABCB11 916/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.