⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129875 | 0.74 | — | — | |
| SCHEMBL4651248 | 0.74 | — | — | |
| SCHEMBL19359843 | 0.73 | — | — | |
| SCHEMBL4683534 | 0.71 | ESR1 (0.42) | — | |
| SCHEMBL4582881 | 0.70 | MAOB (0.47) | — | |
| SCHEMBL25481631 | 0.69 | — | — | |
| SCHEMBL4562889 | 0.69 | SRC (0.38) | — | |
| SCHEMBL13309150 | 0.67 | SRC (0.37) | — | |
| SCHEMBL2544808 | 0.65 | LMNA (0.55) | — | |
| SCHEMBL29942439 | 0.65 | LMNA (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11376334-B2 | Hydrazinyl-substituted heteroaryl compounds and methods for producing a conjugate | R.P. SCHERER TECHNOLOGIES, LLC (US) | 2022-07-05 | — | — | US | disclosed |
| US-20200405876-A1 | Hydrazinyl-Substituted Heteroaryl Compounds and Methods for Producing a Conjugate | ARES CAPITAL CORPORATION, AS COLLATERAL AGENT | 2020-12-31 | — | — | US | disclosed |
| US-10758628-B2 | Hydrazinyl-substituted heteroaryl compounds and methods for producing a conjugate | R.P. SCHERER TECHNOLOGIES, LLC (US) | 2020-09-01 | — | — | US | disclosed |
| US-20190192680-A1 | Hydrazinyl-Substituted Heteroaryl Compounds and Methods for Producing a Conjugate | REDWOOD BIOSCIENCE, INC. | 2019-06-27 | — | — | US | disclosed |
| US-10195283-B2 | Hydrazinyl-substituted heteroaryl compounds and methods for producing a conjugate | R.P. SCHERER TECHNOLOGIES, LLC (US) | 2019-02-05 | — | — | US | disclosed |
| US-20170266302-A1 | Hydrazinyl-Substituted Heteroaryl Compounds and Methods for Producing a Conjugate | R.P. SCHERER TECHNOLOGIES, LLC | 2017-09-21 | — | — | US | disclosed |
| EP-1399156-B1 | ALKYLIDENE PIRAZOLIDINEDIONE DERIVATIVES AND THEIR USE FOR TREATING DIABETES AND OBESITY | APPLIED RESEARCH SYSTEMS (AN) | 2006-11-22 | — | — | EP | disclosed |
| US-20040220188-A1 | Alkylidene pyrazolidinedione derivatives | LABORATOIRES SERONO SA (CH) | 2004-11-04 | — | — | US | disclosed |
| EP-1399156-A2 | ALKYLIDENE PIRAZOLIDINEDIONE DERIVATIVES AND THEIR USE FOR TREATING DIABETES AND OBESITY | Applied Research Systems ARS Holding N.V. (AN) | 2004-03-24 | — | — | EP | disclosed |
| WO-2002102359-A2 | ALKYLIDENE PYRAZOLIDINEDIONE DERIVATIVES AND USE FOR TREATING DIABETES AND OBESITY | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2002-12-27 | — | — | WO | disclosed |