Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 9/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13309150 | 0.92 | SRC (0.37) | SRCERN1GRIA1GRIA2GRIA3 | |
| SCHEMBL28063870 | 0.75 | EGFR (0.47) | SRCERN1KDM4ETDP1EGFR | |
| SCHEMBL28063924 | 0.75 | EGFR (0.61) | SRCERN1MEN1LMNAKMT2A | |
| SCHEMBL5530908 | 0.75 | SRC (0.41) | SRCERN1MEN1KMT2AKDM4E | |
| SCHEMBL5527536 | 0.75 | TYR (0.40) | ERN1TRIM24TRIM33 | |
| SCHEMBL16180715 | 0.74 | SRC (0.34) | SRCERN1MEN1LMNAKMT2A | |
| SCHEMBL605656 | 0.73 | SRC (0.51) | SRCERN1MEN1LMNAKMT2A | |
| SCHEMBL16273309 | 0.73 | ERN1 (0.57) | SRCERN1MEN1LMNAKMT2A | |
| SCHEMBL15359783 | 0.73 | SRC (0.40) | SRCERN1MEN1LMNAKMT2A | |
| SCHEMBL26655793 | 0.73 | ERN1 (0.57) | SRCERN1ALDH1A1TDP1TRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2279291-B1 | COFERONS AND METHODS OF MAKING AND USING THEM | UNIV CORNELL (US) | 2019-07-03 | — | — | EP | disclosed |
| US-9943603-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |
| US-9943603-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |
| US-20150105553-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-04-16 | — | — | US | disclosed |
| US-20150105553-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-04-16 | — | — | US | disclosed |
| US-8853185-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2014-10-07 | — | — | US | disclosed |
| US-8853185-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2014-10-07 | — | — | US | disclosed |
| US-20110263688-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | PURDUE RESEARCH FOUNDATION (US) | 2011-10-27 | — | — | US | disclosed |
| US-20110263688-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | PURDUE RESEARCH FOUNDATION (US) | 2011-10-27 | — | — | US | disclosed |
| WO-2009126290-A2 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2009-10-15 | — | — | WO | disclosed |
| WO-2009126290-A2 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2009-10-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105553-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | MYOF, TNFSF11, F13B | SRC 2456/4885ERN1 4183/4885GRIA1 2326/4885 |
| US-20110263688-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | MYOF, FTH1, TFRC | SRC 2227/4885ERN1 4324/4885GRIA1 2573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.