Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40530 | 0.86 | HSPB1 (0.53) | ALDH1A1LTA4HPTGS2KDM4ELMNA | |
| SCHEMBL9158141 | 0.82 | ALDH1A1 (0.67) | ALDH1A1LTA4HPTGS2KDM4EPGR | |
| SCHEMBL9356592 | 0.82 | ALDH1A1 (0.67) | ALDH1A1LTA4HPTGS2KDM4EPGR | |
| SCHEMBL15472357 | 0.80 | ALDH1A1 (0.54) | ALDH1A1LTA4HPTGS2KDM4ENPY5R | |
| SCHEMBL1701431 | 0.79 | TSHR (0.53) | ALDH1A1LMNAMEN1MAPTKMT2A | |
| SCHEMBL9214229 | 0.79 | ALDH1A1 (0.73) | ALDH1A1LTA4HPTGS2KDM4EPGR | |
| SCHEMBL4203388 | 0.79 | TSHR (0.67) | ALDH1A1LTA4HPTGS2KDM4ECYP2C9 | |
| SCHEMBL9687087 | 0.78 | ALDH1A1 (0.58) | ALDH1A1LTA4HPTGS2KDM4ENPY5R | |
| SCHEMBL8775401 | 0.78 | ALDH1A1 (0.61) | ALDH1A1LTA4HPTGS2KDM4EPGR | |
| SCHEMBL30042572 | 0.78 | ALDH1A1 (0.61) | ALDH1A1LTA4HPTGS2KDM4EPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638943-A2 | NOVEL IMIDAZOLE DERIVATIVES, THE PRODUCTION THEREOF, AND THE USE OF THE SAME AS A MEDICAMENT | Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004106307-A2 | NOVEL IMIDAZOLE DERIVATIVES, THE PRODUCTION THEREOF, AND THE USE OF THE SAME AS A MEDICAMENT | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2004-12-09 | — | — | WO | disclosed |