Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 2/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 3/20 | 0.43 |
| ▸ | METAP1 | P53582 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4242763 | 0.83 | S1PR2 (0.45) | S1PR2S1PR1S1PR3ANPEPERAP1 | |
| SCHEMBL4245142 | 0.83 | S1PR2 (0.45) | S1PR2S1PR1S1PR3ANPEPERAP1 | |
| SCHEMBL4248108 | 0.83 | S1PR2 (0.45) | S1PR2S1PR1S1PR3ANPEPERAP1 | |
| SCHEMBL4250067 | 0.83 | S1PR2 (0.45) | S1PR2S1PR1S1PR3ANPEPERAP1 | |
| SCHEMBL4250599 | 0.83 | S1PR2 (0.45) | S1PR2S1PR1S1PR3ANPEPERAP1 | |
| SCHEMBL2486010 | 0.76 | ANPEP (0.49) | ANPEPERAP1ERAP2METAP2METAP1 | |
| Sulfuric Acid SCHEMBL1605647 | 0.76 | BLM (0.55) | ANPEPERAP1ERAP2METAP2METAP1 | |
| SCHEMBL8884009 | 0.76 | CSNK1E (0.46) | ANPEPERAP1ERAP2METAP2METAP1 | |
| SCHEMBL4247113 | 0.75 | ENPEP (0.46) | ANPEP | |
| Hydrochloric Acid SCHEMBL6891198 | 0.75 | ANPEP (0.47) | ANPEPERAP1ERAP2METAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646659-A2 | IMPROVED PHARMACEUTICAL DRUG CANDIDATES AND METHODS FOR PREPARATION THEREOF | Neurochem (International) Limited (CH) | 2006-04-19 | — | — | EP | disclosed |
| WO-2004113391-A2 | IMPROVED PHARMACEUTICAL DRUG CANDIDATES AND METHODS FOR PREPARATION THEREOF | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2004-12-29 | — | — | WO | disclosed |