SCHEMBL385022

SCHEMBL385022

NC1CCCCN1C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.36
HPGD P15428 1/20 0.36
DPP7 Q9UHL4 3/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
CHRM2 P08172 8/20 0.35
CHRM4 P08173 8/20 0.35
CHRM5 P08912 8/20 0.35
CHRM1 P11229 8/20 0.35
CHRM3 P20309 8/20 0.35
DPP4 P27487 5/20 0.35
DPP8 Q6V1X1 2/20 0.35
DPP9 Q86TI2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4179330 1.00 GAA (0.36) GAAHPGDDPP7CA12CA1
SCHEMBL30443171 0.98 CHRM2 (0.37) GAAHPGDDPP7CA12CA1
SCHEMBL21773024 0.93
SCHEMBL19408961 0.93
SCHEMBL3488662 0.93
Glycine SCHEMBL4955985 0.90 DPP4 (0.39) DPP7CHRM2CHRM4CHRM5CHRM1
Alanine SCHEMBL4955495 0.87 DPP4 (0.44) DPP7CHRM2CHRM4CHRM5CHRM1
SCHEMBL21296547 0.83
Serine SCHEMBL4955395 0.83 DPP7 (0.40) DPP7CHRM2CHRM4CHRM5CHRM1
SCHEMBL4002060 0.82 GAA (0.36) GAAHPGDDPP7CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 489 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7439226-B2 Serine protease inhibitors THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2008-10-21 US claimed
EP-1761554-A2 PEPTIDE ANTIBIOTICS AND METHODS FOR MAKING SAME Biosource Pharm, Inc. (US) 2007-03-14 EP claimed
WO-2006083317-A2 PEPTIDE ANTIBIOTICS AND METHODS FOR MAKING SAME BIOSOURCE PHARM, INC. (US) 2006-08-10 WO claimed
WO-2006043933-A1 SERINE PROTEASE INHIBITORS THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2006-04-27 WO claimed
US-20050130883-A1 Serine protease inhibitors THE GOV. OF THE USA AS REPRESENTED BY THE SECRETARY OF THE DEPT. OF HEALTH & HUMAN SERVICES 2005-06-16 US claimed
US-20260055150-A1 GRAIL-1 PEPTIDE PRODUCTS AND METHODS UNIV MICHIGAN (US) 2026-02-26 US disclosed
EP-4680108-A1 PEPTIDE MULTIMER PRODUCTS AND METHODS The Regents of The University of Michigan (US) 2026-01-21 EP disclosed
EP-4658644-A1 2-(PYRIDAZIN-3-YL)-5-(TRIFLUOROMETHYL)PHENOLS AS NLRP3 INHIBITORS Janssen Pharmaceutica NV (BE) 2025-12-10 EP disclosed
US-20250263685-A1 OLIGOSACCHARIDES COMPRISING AN AMINOOXY GROUP AND CONJUGATES THEREOF GENZYME CORPORATION 2025-08-21 US disclosed
US-20250263439-A1 HETERODIMERIC PEPTIDE REAGENTS AND METHODS THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2025-08-21 US disclosed
EP-3660040-B1 INSULIN RECEPTOR PARTIAL AGONISTS MERCK SHARP & DOHME LLC (US) 2025-06-18 EP disclosed
EP-4565333-A2 GRAIL-1 PEPTIDE PRODUCTS AND METHODS Regents of the University of Michigan (US) 2025-06-11 EP disclosed
WO-2006043933-A1 SERINE PROTEASE INHIBITORS THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2006-04-27 WO disclosed
WO-2005060949-A2 SELECTIVE NOREPINEPHRINE REUPTAKE INHIBITORS FOR THE TREATMENT OF HOT FLASHES, IMPULSE CONTROL DISORDERS AND PERSONALITY CHANGE DUE TO A GENERAL MEDICAL CONDITION ELI LILLY AND COMPANY (US) 2005-07-07 WO disclosed
US-20050148515-A1 Peptidomimetics; determining ability to bind growth hormone secretagogue; ghrelin agonists; appetite stimulation; dietetics IPSEN PHARMA S.A.S. (FR) 2005-07-07 US disclosed
US-20050130883-A1 Serine protease inhibitors THE GOV. OF THE USA AS REPRESENTED BY THE SECRETARY OF THE DEPT. OF HEALTH & HUMAN SERVICES 2005-06-16 US disclosed
US-6806273-B1 5-THIO-THIAZOLO(4,5-D)PYRIMIDIN-7-YL DERIVATIVES; CHEMOKINE RECEPTOR (ESPECIALLY CXCR2) ACTIVITY MODULATORS ASTRAZENECA AB (SE) 2004-10-19 US disclosed
US-20040059088-A1 Short amphipathic peptides with activity against bacteria and intracellular pathogens MCLAUGHLIN MARK L (US) 2004-03-25 US disclosed
US-6566334-B1 For therapy of bacterial infection BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE 2003-05-20 US disclosed
CN-1177299-A Certain 1, 4, 5 -tri- substituted imidazole compounds useful as cytokine SMITHKLINE BEECHAM CORP (US) 1998-03-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260055150-A1 GRAIL-1 PEPTIDE PRODUCTS AND METHODS TP53, TP53BP1, DDIT3 GAA 3459/4885HPGD 4316/4885DPP7 4473/4885
US-20050148515-A1 Peptidomimetics; determining ability to bind growth hormone secretagogue; ghrelin agonists; appetite stimulation; dietetics GIPR, GHSR, GHRHR GAA 4561/4885HPGD 2609/4885DPP7 120/4885
US-20250263439-A1 HETERODIMERIC PEPTIDE REAGENTS AND METHODS ERBB2, EGFR, ERBB3 GAA 2999/4885HPGD 2739/4885DPP7 2248/4885
US-20040059088-A1 Short amphipathic peptides with activity against bacteria and intracellular pathogens VIP, MDK, HM13 GAA 1946/4885HPGD 3821/4885DPP7 249/4885
US-20250263685-A1 OLIGOSACCHARIDES COMPRISING AN AMINOOXY GROUP AND CONJUGATES THEREOF MAN2B1, MAN1B1, GAA GAA 3/4885HPGD 3804/4885DPP7 692/4885
US-20050130883-A1 Serine protease inhibitors PRSS1, TASP1, METAP1 GAA 1191/4885HPGD 2388/4885DPP7 173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.