Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 6/20 | 0.44 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.40 |
| ▸ | ACP1 | P24666 | 3/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5742833 | 0.90 | MCHR1 (0.48) | MCHR1AGPAT2TLR8TERTDOT1L | |
| SCHEMBL5741006 | 0.88 | AGPAT2 (0.42) | MCHR1AGPAT2PDE4BACP1HRH4 | |
| SCHEMBL5742792 | 0.85 | AGPAT2 (0.59) | AGPAT2ACP1PDPK1HRH4TERT | |
| SCHEMBL5742344 | 0.84 | MCHR1 (0.44) | MCHR1AGPAT2TLR8ACP1PDPK1 | |
| SCHEMBL5743466 | 0.84 | AGPAT2 (0.42) | MCHR1AGPAT2PDE4BACP1HRH4 | |
| SCHEMBL5742859 | 0.83 | AGPAT2 (0.63) | AGPAT2ACP1PDPK1HRH4 | |
| SCHEMBL5743245 | 0.83 | AGPAT2 (0.45) | AGPAT2ACP1HRH4 | |
| SCHEMBL5741907 | 0.82 | MCHR1 (0.44) | MCHR1AGPAT2TLR8PDPK1TERT | |
| SCHEMBL5742786 | 0.82 | AGPAT2 (0.64) | AGPAT2ACP1PDPK1HRH4 | |
| SCHEMBL5742888 | 0.82 | AGPAT2 (0.64) | AGPAT2ACP1PDPK1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339706-B1 | N-TYPE CALCIUM CHANNEL ANTAGONISTS FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2006-04-19 | — | — | EP | disclosed |