Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 2/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2748162 | 0.98 | NR4A1 (0.50) | NR4A1NR4A2NR4A3ALBKDM4E | |
| Water SCHEMBL5740328 | 0.95 | NR4A1 (0.47) | NR4A1NR4A2NR4A3ALBKDM4E | |
| SCHEMBL28575439 | 0.80 | NR4A1 (0.70) | NR4A1NR4A2NR4A3ALBKDM4E | |
| SCHEMBL3389447 | 0.79 | NR4A1 (0.53) | NR4A1NR4A2NR4A3ALBKDM4E | |
| SCHEMBL30388521 | 0.79 | NR4A1 (0.53) | NR4A1NR4A2NR4A3ALBKDM4E | |
| SCHEMBL2748381 | 0.78 | LMNA (0.51) | NR4A2KDM4EALDH1A1CA12CA1 | |
| SCHEMBL10012443 | 0.78 | NR4A1 (0.67) | NR4A1NR4A2NR4A3ALBKDM4E | |
| SCHEMBL11857852 | 0.78 | NR4A1 (0.67) | NR4A1NR4A2NR4A3ALBKDM4E | |
| SCHEMBL29406795 | 0.78 | NR4A1 (0.73) | NR4A1NR4A2NR4A3ALBKDM4E | |
| SCHEMBL27985 | 0.78 | NR4A1 (0.73) | NR4A1NR4A2NR4A3ALBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713484-A2 | COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005070891-A2 | COMPOUNDS AND METHODS OF USE | AMGEN INC (US) | 2005-08-04 | — | — | WO | disclosed |