Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 11/20 | 0.36 |
| ▸ | RCOR1 | Q9UKL0 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 5/20 | 0.32 |
| ▸ | MAOB | P27338 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5197214 | 0.79 | MAOA (0.47) | KDM1AMAOAMAOB | |
| SCHEMBL9779916 | 0.74 | LMNA (0.42) | KDM1ARCOR1ALDH1A1LMNACYP19A1 | |
| Hydrochloric Acid SCHEMBL11692957 | 0.72 | LMNA (0.41) | KDM1ARCOR1ALDH1A1LMNACYP19A1 | |
| SCHEMBL30695906 | 0.70 | DDB1 (0.40) | KDM1ARCOR1ALDH1A1LMNACYP19A1 | |
| SCHEMBL38656156 | 0.70 | KDM1A (0.45) | KDM1ARCOR1ALDH1A1LMNACYP19A1 | |
| SCHEMBL20707778 | 0.70 | KDM1A (0.45) | KDM1ARCOR1ALDH1A1LMNACYP19A1 | |
| SCHEMBL20707745 | 0.70 | KDM1A (0.45) | KDM1ARCOR1ALDH1A1LMNACYP19A1 | |
| SCHEMBL22335046 | 0.68 | KDM1A (0.65) | KDM1ARCOR1ALDH1A1LMNACYP19A1 | |
| Hydrochloric Acid SCHEMBL31645588 | 0.68 | KDM1A (0.39) | KDM1ARCOR1ALDH1A1LMNACYP19A1 | |
| SCHEMBL15780120 | 0.67 | KDM1A (0.70) | KDM1ARCOR1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646621-A2 | NOVEL AZAHETEROCYCLIC AMIDES USEFUL FOR TREATING PAIN | Abbott Laboratories (US) | 2006-04-19 | — | — | EP | disclosed |
| WO-2005007642-A2 | NOVEL AZAHETEROCYCLIC AMIDES USEFUL FOR TREATING PAIN | ABBOTT LABORATORIES (US) | 2005-01-27 | — | — | WO | disclosed |