Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 6/20 | 0.50 |
| ▸ | AGPAT2 | O15120 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.44 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5740529 | 0.96 | MCHR1 (0.53) | MCHR1AGPAT2ROCK2ACP1TRPV1 | |
| SCHEMBL5740849 | 0.91 | MCHR1 (0.51) | MCHR1AGPAT2KDM4EROCK2ACP1 | |
| SCHEMBL5742330 | 0.91 | MCHR1 (0.51) | MCHR1AGPAT2KDM4EROCK2ACP1 | |
| SCHEMBL5742875 | 0.91 | AGPAT2 (0.57) | MCHR1AGPAT2KDM4EROCK2ACP1 | |
| SCHEMBL5741991 | 0.91 | AGPAT2 (0.57) | MCHR1AGPAT2KDM4EROCK2ACP1 | |
| SCHEMBL5740176 | 0.89 | AGPAT2 (0.56) | MCHR1AGPAT2ROCK2ACP1DOT1L | |
| SCHEMBL5742700 | 0.89 | MCHR1 (0.52) | MCHR1AGPAT2ROCK2ACP1TRPV1 | |
| SCHEMBL5743755 | 0.88 | KDM4E (0.55) | MCHR1AGPAT2KDM4EROCK2ACP1 | |
| SCHEMBL5741808 | 0.88 | MCHR1 (0.50) | MCHR1AGPAT2KDM4EROCK2ACP1 | |
| SCHEMBL5741794 | 0.88 | MCHR1 (0.50) | MCHR1AGPAT2KDM4EROCK2ACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339706-B1 | N-TYPE CALCIUM CHANNEL ANTAGONISTS FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2006-04-19 | — | — | EP | disclosed |