Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGPAT2 | O15120 | 10/20 | 0.57 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5741991 | 1.00 | AGPAT2 (0.57) | AGPAT2MCHR1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL5740529 | 0.95 | MCHR1 (0.53) | AGPAT2MCHR1ROCK2ACP1TRPV1 | |
| SCHEMBL5741862 | 0.91 | AGPAT2 (0.57) | AGPAT2MCHR1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL5741884 | 0.91 | AGPAT2 (0.52) | AGPAT2MCHR1ROCK2ACP1TRPV1 | |
| SCHEMBL5741026 | 0.91 | AGPAT2 (0.52) | AGPAT2MCHR1ROCK2ACP1TRPV1 | |
| SCHEMBL5740460 | 0.91 | MCHR1 (0.50) | AGPAT2MCHR1KDM4EROCK2CYP3A4 | |
| SCHEMBL5744288 | 0.89 | KDM4E (0.56) | AGPAT2MCHR1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL5740563 | 0.89 | AGPAT2 (0.52) | AGPAT2MCHR1ROCK2ACP1TRPV1 | |
| SCHEMBL5740139 | 0.89 | AGPAT2 (0.60) | AGPAT2KDM4EALDH1A1HSD17B10ROCK2 | |
| SCHEMBL5742700 | 0.88 | MCHR1 (0.52) | AGPAT2MCHR1ROCK2ACP1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339706-B1 | N-TYPE CALCIUM CHANNEL ANTAGONISTS FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2006-04-19 | — | — | EP | disclosed |