Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2985948 | 0.89 | CCR2 (1.00) | CCR2 | |
| SCHEMBL2988924 | 0.89 | CCR2 (0.88) | CCR2 | |
| SCHEMBL2993760 | 0.89 | CCR2 (0.88) | CCR2 | |
| SCHEMBL5742691 | 0.88 | CCR2 (0.81) | CCR2 | |
| SCHEMBL5742686 | 0.88 | CCR2 (0.81) | CCR2 | |
| Trifluoroacetic Acid SCHEMBL2985848 | 0.86 | CCR2 (0.94) | CCR2 | |
| Trifluoroacetic Acid SCHEMBL2993694 | 0.86 | CCR2 (0.83) | CCR2 | |
| Trifluoroacetic Acid SCHEMBL3082263 | 0.86 | CCR2 (0.83) | CCR2 | |
| SCHEMBL2979660 | 0.85 | CCR2 (0.73) | CCR2 | |
| SCHEMBL5854176 | 0.85 | CCR2 (0.73) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1483241-A4 | CYCLIC DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL MYERS SQUIBB CO (US) | 2006-12-13 | — | — | EP | claimed |
| EP-1483241-A2 | CYCLIC DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Bristol-Myers Squibb Company (US) | 2004-12-08 | — | — | EP | claimed |
| WO-2003075853-A2 | CYCLIC DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-09-18 | — | — | WO | claimed |