Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 7/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RUVBL1 | Q9Y265 | 1/20 | 0.43 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | BCR | P11274 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5741057 | 0.92 | ACP1 (0.57) | ACP1MAPTTP53HPGDALOX15 | |
| SCHEMBL5741066 | 0.91 | ACP1 (0.51) | ACP1ABCG2MAPTTP53HPGD | |
| SCHEMBL5742700 | 0.91 | MCHR1 (0.52) | ACP1ABCG2MAPTMCHR1LMNA | |
| SCHEMBL5741286 | 0.89 | MAPT (0.53) | ACP1ABCG2MAPTTP53HPGD | |
| SCHEMBL5742142 | 0.89 | MAPT (0.57) | ACP1MAPTTP53HPGDALOX15 | |
| SCHEMBL5741862 | 0.88 | AGPAT2 (0.57) | ABCG2MAPTTP53HSD17B10KDM4E | |
| SCHEMBL5743423 | 0.88 | MAPT (0.48) | ACP1ABCG2MAPTTP53HPGD | |
| SCHEMBL5743353 | 0.88 | RAB9A (0.52) | ACP1MAPTTP53HPGDALOX15 | |
| SCHEMBL5741949 | 0.87 | TP53 (0.49) | ACP1ABCG2MAPTTP53HPGD | |
| SCHEMBL5740501 | 0.86 | AGPAT2 (0.52) | ACP1MAPTTP53HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339706-B1 | N-TYPE CALCIUM CHANNEL ANTAGONISTS FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2006-04-19 | — | — | EP | disclosed |