Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 9/20 | 0.44 |
| ▸ | GRB2 | P62993 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | GRM8 | O00222 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methionine SCHEMBL5694625 | 0.85 | BLM (0.46) | BLMSLC7A5KIF11ESR1GRM8 | |
| Tyrosine SCHEMBL28430992 | 0.80 | SLC7A5 (0.71) | SLC7A5GRB2 | |
| Tyrosine SCHEMBL180587 | 0.80 | SLC7A5 (0.71) | SLC7A5GRB2 | |
| Tyrosine SCHEMBL180585 | 0.80 | SLC7A5 (0.71) | SLC7A5GRB2 | |
| SCHEMBL24253146 | 0.80 | BLM (0.62) | BLMSLC7A5ESR1 | |
| SCHEMBL11226560 | 0.80 | BLM (0.62) | BLMSLC7A5ESR1 | |
| SCHEMBL1906339 | 0.80 | BLM (0.62) | BLMSLC7A5ESR1 | |
| Racemethionine SCHEMBL14248767 | 0.77 | KIF11 (0.51) | SLC7A5KIF11GRM8GRM4 | |
| Methionine SCHEMBL14248774 | 0.77 | KIF11 (0.51) | SLC7A5KIF11GRM8GRM4 | |
| Tyrosine SCHEMBL1724134 | 0.77 | SLC7A5 (0.60) | SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658264-A2 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | Neurochem (International) Limited (CH) | 2006-05-24 | — | — | EP | disclosed |
| WO-2004113277-A2 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2004-12-29 | — | — | WO | disclosed |