Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.67 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.63 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.54 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8408714 | 0.92 | ALDH1A1 (0.69) | LTA4HEPHX2ALDH1A1RECQLFFAR1 | |
| SCHEMBL34023 | 0.92 | ALDH1A1 (0.60) | LTA4HEPHX2ALDH1A1RECQLFFAR1 | |
| SCHEMBL4520940 | 0.89 | ALDH1A1 (0.66) | LTA4HEPHX2ALDH1A1RECQLFFAR1 | |
| SCHEMBL24041796 | 0.89 | FFAR1 (0.68) | LTA4HEPHX2ALDH1A1RECQLFFAR1 | |
| SCHEMBL14463874 | 0.89 | LTA4H (0.77) | LTA4HEPHX2ALDH1A1RECQLFFAR1 | |
| SCHEMBL19102211 | 0.89 | ALDH1A1 (0.69) | LTA4HEPHX2ALDH1A1RECQLFFAR1 | |
| SCHEMBL4165319 | 0.87 | FFAR1 (0.69) | LTA4HEPHX2ALDH1A1FFAR1DRD2 | |
| SCHEMBL4990243 | 0.86 | LTA4H (0.62) | LTA4HEPHX2ALDH1A1RECQLFFAR1 | |
| SCHEMBL8500544 | 0.86 | FFAR1 (0.67) | LTA4HEPHX2ALDH1A1FFAR1DRD2 | |
| SCHEMBL4659369 | 0.86 | LTA4H (0.73) | LTA4HEPHX2ALDH1A1FFAR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5573754-A | SUNSCREENS | RICHARDSON-VICKS INC. (US) | 1996-11-12 | — | — | US | claimed |
| EP-1074244-B1 | Topical composition comprising a tocopherol compound | DSM IP ASSETS BV (NL) | 2006-03-08 | — | — | EP | disclosed |
| EP-1074244-A2 | Topical composition comprising a tocopherol compound | F. HOFFMANN-LA ROCHE AG (CH) | 2001-02-07 | — | — | EP | disclosed |