Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16955799 | 0.88 | ALDH1A1 (0.38) | ALDH1A1NFE2L2ERN1 | |
| SCHEMBL21397242 | 0.88 | ERN1 (0.47) | ALDH1A1TSHRERN1TDP1MEN1 | |
| SCHEMBL466535 | 0.87 | NFE2L2 (0.44) | ALDH1A1NFE2L2ERN1 | |
| SCHEMBL29620247 | 0.87 | NFE2L2 (0.44) | ALDH1A1NFE2L2ERN1 | |
| SCHEMBL2945596 | 0.83 | ALDH1A1 (0.38) | ALDH1A1NFE2L2LMNA | |
| SCHEMBL16955108 | 0.83 | ALDH1A1 (0.38) | ALDH1A1NFE2L2 | |
| SCHEMBL9245053 | 0.83 | ALDH1A1 (0.60) | ALDH1A1NFE2L2TSHRTDP1MEN1 | |
| SCHEMBL1466885 | 0.83 | ALDH1A1 (0.38) | ALDH1A1NFE2L2TSHRTDP1 | |
| SCHEMBL16956536 | 0.83 | ERN1 (0.40) | ALDH1A1ERN1TDP1LMNABLM | |
| SCHEMBL7542304 | 0.83 | ALDH1A1 (0.38) | ALDH1A1NFE2L2TSHRTDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| US-8969498-B2 | Compositions and method of inhibiting polymerization of vinyl-aryl monomers | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-03-03 | — | — | US | disclosed |
| CN-103124745-B | Compositions and method of inhibiting polymerization of vinyl-aryl monomers | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-10-29 | — | — | CN | disclosed |
| EP-2585490-B1 | COMPOSITIONS AND METHOD OF INHIBITING POLYMERIZATION OF VINYL-ARYL MONOMERS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-07-02 | — | — | EP | disclosed |
| US-20130158203-A1 | COMPOSITIONS AND METHOD OF INHIBITING POLYMERIZATION OF VINYL-ARYL MONOMERS | CARNEGIE MELLON UNIVERSITY (US) | 2013-06-20 | — | — | US | disclosed |
| CN-103124745-A | Compositions and method of inhibiting polymerization of vinyl-aryl monomers | DOW GLOBAL TECHNOLOGIES LLC | 2013-05-29 | — | — | CN | disclosed |
| EP-2585490-A1 | COMPOSITIONS AND METHOD OF INHIBITING POLYMERIZATION OF VINYL-ARYL MONOMERS | Dow Global Technologies LLC (US) | 2013-05-01 | — | — | EP | disclosed |
| WO-2012018650-A1 | COMPOSITIONS AND METHOD OF INHIBITING POLYMERIZATION OF VINYL-ARYL MONOMERS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158203-A1 | COMPOSITIONS AND METHOD OF INHIBITING POLYMERIZATION OF VINYL-ARYL MONOMERS | PCNA, MKI67, VCL | ALDH1A1 1937/4885NFE2L2 3684/4885TSHR 4782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.